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About 1,225,585 results

Chronic kidney disease: summary of updated NICE guidance.
https://doi.org/10.1136/bmj.n1992
BMJ (Clinical Research Ed.); Martinez YV, Benett I et. al.

Sep 8th, 2021 - Chronic kidney disease: summary of updated NICE guidance.|2021|Martinez YV,Benett I,Lewington AJP,Wierzbicki AS, ,|therapeutic use,therapeutic use,urine,diagnosis,physiopathology,therapy,therapeutic use,

Coronavirus induces diabetic macrophage-mediated inflammation via SETDB2.
https://doi.org/10.1073/pnas.2101071118
Proceedings of the National Academy of Sciences of the Un... Melvin WJ, Audu CO et. al.

Sep 5th, 2021 - COVID-19 induces a robust, extended inflammatory "cytokine storm" that contributes to an increased morbidity and mortality, particularly in patients with type 2 diabetes (T2D). Macrophages are a key innate immune cell population responsible for the cytokine storm that has been shown, in T2D, to promote excess inflammation in response to infection. Using peripheral monocytes and sera from human ...

Characteristics and mortality in primary Sjögren syndrome-related interstitial lung dis...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415932
Medicine Gao H, Sun Y et. al.

Sep 4th, 2021 - Aim of the study was to determine the characteristics and prognosis, and to identify the risk factors for mortality in patients with primary Sjögren syndrome (pSS) with interstitial lung disease (pSS-ILD).A total of 1422 patients with SS were screened and 178 patients with pSS-ILD were recruited. The medical records and outcomes were retrospectively reviewed. Overall survival and case control s...

Efficacy and safety of dual vs single renin-angiotensin-aldosterone system blockade in ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415955
Medicine Zhao M, Qu H et. al.

Sep 4th, 2021 - To lower albuminuria and to achieve blood pressure (BP) goals, dual renin-angiotensin-aldosterone system (RAAS) inhibitors are sometimes used in clinical practice for the treatment of CKD. However, the efficacy and safety of dual RAAS blockade therapy remains controversial. PubMed, EMBASE, and Cochrane Library were searched, and random effects model was used to calculate the effect sizes of eli...

Clinical characteristics of cirrhosis patients with umbilical vein recanalization: A re...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415999
Medicine Shi Q, Xiong K et. al.

Sep 4th, 2021 - Umbilical Vein Recanalization (UVR) may occur in patients with long-standing portal hypertension and liver cirrhosis. This study aimed to investigate the clinical significance of UVR.Medical records of a cohort of patients with cirrhosis (n = 247) who were hospitalized at the Digestive Medicine Center of the Second Affiliated Hospital of Nanchang University from January 2012 to October 2015 wer...

A retrospective study on the preventive effect of statin after carotid artery stenting.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416008
Medicine Liu W, Zhao XF et. al.

Sep 4th, 2021 - This retrospective study appraised the preventive effect of statin after carotid artery stenting (CAS).Records were extracted for 100 patients with CAS surgery indicator, aged between 20 and 75 years old, and treated for statin. The cohort study included treatment group (statin and routine treatment) and control group (routine treatment), each group 50 patients. Outcomes consisted of degree of ...

Physical exercise keeps the brain connected by increasing white matter integrity in hea...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415959
Medicine Bashir S, Al-Sultan F et. al.

Sep 4th, 2021 - Physical exercise leads to structural changes in the brain. However, it is unclear whether the initiation or continuous practice of physical exercise causes this effect and whether brain connectivity benefits from exercise. We examined the effect of 6 months of exercise on the brain in participants who exercise regularly (n = 25) and in matched healthy controls (n = 20). Diffusion tensor imagin...

Longitudinal assessment of amyloid-beta deposition in initially amyloid-negative non-de...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416000
Medicine Hatashita S, Wakebe D

Sep 4th, 2021 - This study aimed to assess the longitudinal changes in amyloid beta (Aβ) deposition in cortical regions with [11C]-PIB PET in initially amyloid-negative non-demented subjects and evaluate whether amyloid-negative subjects convert to amyloid-positive.Sixteen cognitively normal (CN) and 7 mild cognitive impairment (MCI) subjects (aged 60-75 years), who were amyloid-negative at baseline, underwent...

Refinement of recto-sigmoid colon vaginoplasty using a three-dimensional laparoscopic t...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416006
Medicine Kim JK, Na W et. al.

Sep 4th, 2021 - To investigate the feasibility, safety, and outcomes of three-dimensional (3D) laparoscopic vaginoplasty with a rectosigmoid colon flap for vaginal reconstruction.Following appropriate preoperative patient counseling, 17 consecutive patients underwent vaginoplasty using a 3D laparoscopic system. Perioperative and postoperative outcomes were retrospectively evaluated.Between September 2016 and F...

Successful endovascular therapy for an adolescent patient with cerebral venous sinus th...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415943
Medicine Peng T, Zhang Z et. al.

Sep 4th, 2021 - Cerebral venous sinus thrombosis associated with protein S deficiency is rare in adolescent patients and has high disability and fatality.Patient concerns: A 15-year-old male student presented in the hospital with sudden headache, nausea, and vomiting and was diagnosed with protein S deficiency by gene testing. Cerebral venous sinus thrombosis due to protein S deficiency was diagnosed in this a...

The effectiveness of corticosteroid injection and splint in diabetic de Quervain's teno...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415982
Medicine Başar B, Aybar A et. al.

Sep 4th, 2021 - There is no clear information on the efficacy of corticosteroids, and splints in the treatment of patients with diabetes mellitus (DM). The aim of this study was to compare the outcomes of isolated corticosteroid injection therapy with splint treatment with corticosteroid injection in patients with and without DM. 84 diabetics, and 84 healthy patients with a diagnosis of de Quervain's tenosynov...

Clinical and pathological characteristics of patients with pulmonary inflammatory pseud...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415998
Medicine Chen HC, Fu Q et. al.

Sep 4th, 2021 - To investigate the clinical and pathological characteristics in patients with pulmonary inflammatory pseudotumors (PIP).This retrospective study included 31 patients with PIP from 2001 to 2019. Preoperative computed tomography scan was performed in all patients. Clinical and pathological characteristics were collected and analyzed.Thirty-one patients (16 female and 15 male) were recruited, with...

Prolidase expression in knee osteoarthritis and healthy controls: Observational study.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415933
Medicine Silva-Luna K, Ventura-Ríos L et. al.

Sep 4th, 2021 - Prolidase enzyme activity is important for collagen resynthesis. In late stages of osteoarthritis (OA) its activity is decreased.To evaluate prolidase expression in knees of patients undergoing total arthroplasty for OA, and compare with young people undergoing knee arthroscopy due to traumatic injuries.In this cross-sectional study we included 20 patients with OA grade IV who underwent total k...

Patient with sick sinus syndrome and implanted dual-chamber pacemaker with reduced P-wa...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415954
Medicine Mercik J, Gajek-Marecka A et. al.

Sep 4th, 2021 - A dual-chamber pacemaker (DDD/R) for a sinus node disease is sometimes referred to as a physiological pacemaker as it maintains atrioventricular synchrony, however several clinical trials have proved its inferiority to a nonphysiological single-chamber ventricular back-up pacing. A subject of the study is a 74-year-old woman with a sick sinus syndrome (SSS) and a previously implanted physiologi...

Natural course of hemoglobin level after total knee arthroplasty and the benefit of tra...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415948
Medicine Cho MR, Jun CM et. al.

Sep 4th, 2021 - We retrospectively investigated the natural course of hemoglobin (Hb) level after total knee arthroplasty (TKA) and identified the benefit of tranexamic acid injection at the operation field for unilateral TKA patients who have not received blood transfusions.There were 115 cases conducted by a surgeon who performed TKA without injecting tranexamic acid and 62 cases by another surgeon with inje...

Efficacy and safety of acupuncture combined with Chinese Herbal Medicine for diabetic n...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416003
Medicine Yu Z, Zhang W et. al.

Sep 4th, 2021 - Diabetic nephropathy (DN) is one of the most serious complications in the development of diabetes mellitus, which has become the main cause of end-stage renal disease and one of the main causes of death in diabetic patients. With the prevalence of diabetes, the number of patients at risk for developing DN is increasing, with 20-40 percent of all patients with diabetes at risk for developing DN....

To evaluate the microcirculation of retinochoroid capillary between acute and chronic c...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415977
Medicine Lu H, Wang Z et. al.

Sep 4th, 2021 - To investigate the difference in chorioretinal microcirculation between acute central serous chorioretinopathy (aCSC) and chronic central serous chorioretinopathy (cCSC) using optical coherence tomography angiography.In total, 65 patients previously diagnosed with central serous chorioretinopathy (33 aCSC and 32 cCSC) were included in our cross-sectional study. All patients underwent complete o...

Cardiopulmonary function findings of pediatric patients with patent ductus arteriosus.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415991
Medicine Huang HY, Wang SP et. al.

Sep 4th, 2021 - Transcatheter occlusion and surgical ligation are the treatments of choice for most patent ductus arteriosus (PDA) in children. Fifty-five children who had PDA completed a pulmonary function test and a symptom-limited treadmill exercise test from 2016 to 2018 at 1 medical center in southern Taiwan. The study group was divided into surgical ligation and catheterization groups, which were compare...

Value of shear wave elastography combined with the Toronto clinical scoring system in d...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415960
Medicine Wang F, Zheng M et. al.

Sep 4th, 2021 - To evaluate the diagnostic values of shear wave elastography (SWE) alone and in combination with the Toronto clinical scoring system (TCSS) on diabetic peripheral neuropathy (DPN) in patients with type 2 diabetes mellitus (T2DM).The study included 41 DPN patients, 42 non-DPN patients, and 21 healthy volunteers. Conventional ultrasonography and SWE were performed on the 2 sides of the tibial ner...

Characteristics of lymph node (No.5 and No.6) metastasis and significance of lymph node...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416002
Medicine Zhang X, He XD et. al.

Sep 4th, 2021 - To analyze the characteristics, related risk factors, and prognosis of lymph node metastasis (Number [No.] 5 and No.6) in the group of adenocarcinoma of esophagogastric junction (AEG). The patients with Siewert II AEG who underwent total gastrectomy and D2 lymph node dissection from September 2015 to December 2018 in Lanzhou University Second Hospital were enrolled in this study. The pathologic...