×
About 435,345 results

Examination of Protein Quantity and Protein Distribution across the Day on Ad Libitum Carbohydrate and Fat Intake in Overweight Women
https://academic.oup.com/cdn/article/1/12/e001933/4772174

The effects of meal-specific protein quantity and protein distribution throughout the day on daily food intake are relatively unknown.

Kinetics of viral load and antibody response in relation to COVID-19 severity
https://dm5migu4zj3pb.cloudfront.net/manuscripts/138000/138759/cache/138759.1-20200701111152-covered-253bed37ca4c1ab43d105aefdf7b5536.pdf

The SARS-CoV-2 is the causative agent for COVID-19 pneumonia. Little is known about the 60 kinetics, tissue distribution, cross-reactivity and neutralization antibody response in COVID61 19 patients. Two groups of RT-PCR confirmed COVID-19 patients were enrolled in this study, 62 including 12 severe patients in ICUs who needed mechanical ventilation and 11 mild patients 63 in isolation wards...

E-cigarette Use Among Middle and High School Students — United States, 2020
https://www.cdc.gov/mmwr/volumes/69/wr/mm6937e1.htm?s_cid=mm6937e1_x

The use of any tobacco product by youths is unsafe, including electronic cigarettes (e-cigarettes) (1). Most e-cigarettes contain nicotine, which is highly addictive, can harm the developing adolescent brain, and can increase risk for future addiction to other drugs (1). E-cigarette use has increased considerably among U.S. youths since 2011 (1,2). Multiple factors have contributed to this incr...

Protein Distribution and Muscle-Related Outcomes: Does the Evidence Support the Concept?
https://www.mdpi.com/2072-6643/12/5/1441/htm

There is a shift in thinking about dietary protein requirements from daily requirements to individual meal requirements. Per meal, stimulation of muscle protein synthesis has a saturable dose relationship with the quantity of dietary protein consumed. Protein intake above the saturable dose does not further contribute to the synthetic response; the “excess” amino acids are predominantly oxidize...

Medications: Distribution of Sample Medications in the Practice Setting
https://www.medicalmutual.com/risk/practice-tips/tip/medications-distribution-of-sample-medications-in-the-practice-setting/81

Many physician offices accept sample medications from pharmaceutical drug representatives and dispense them to their patient population. Compliance with providing sample medications to patients in a safe manner requires a significant administrative effort. When the physician office practice dispenses sample medications to its patients, the practice is acting as a pharmacy and is required to fol...

Face mask use in the general population and optimal resource allocation during the COVID-19 pandemic
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426871/

The ongoing novel coronavirus disease (COVID-19) pandemic has already infected millions worldwide and, with no vaccine available, interventions to mitigate transmission are urgently needed. While there is broad agreement that travel restrictions and social distancing are beneficial in limiting spread, recommendations around face mask use are inconsistent. Here, we use mathematical modeling to e...

Epidemiology, treatment and prevention of herpes zoster: A comprehensive review
http://www.ijdvl.com/article.asp?issn=0378-6323;year=2018;volume=84;issue=3;spage=251;epage=262;aulast=Koshy

Herpes zoster is a major health burden that can affect individuals of any age. It is seen more commonly among individuals aged ≥50 years, those with immunocompromised status, and those on immunosuppressant drugs. It is caused by a reactivation of varicella zoster virus infection. Cell-mediated immunity plays a role in this reactivation. Fever, pain, and itch are common symptoms before the onset...

Children and COVID-19: State-Level Data Report
https://services.aap.org/en/pages/2019-novel-coronavirus-covid-19-infections/children-and-covid-19-state-level-data-report/

State-level reports are the best publicly available data on child COVID-19 cases in the United States. The American Academy of Pediatrics and the Children’s Hospital Association are collaborating to collect and share all publicly available data from states on child COVID-19 cases (definition of “child” case is based on varying age ranges reported across states; see report Appendix for details a...

Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019
https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(21)00249-8/fulltext
The Lancet Public Health; GBD 2019 Dementia Forecasting Collaborators

Jan 6th, 2022 - Given the projected trends in population ageing and population growth, the number of people with dementia is expected to increase. In addition, strong evidence has emerged supporting the importance of potentially modifiable risk factors for dementia. Characterising the distribution and magnitude of anticipated growth is crucial for public health planning and resource prioritisation. This study ...

CDC Updates Blood Lead Reference Value for Children
https://www.cdc.gov/media/releases/2021/p1028-blood-lead.html
Centers for Disease Control and Prevention (CDC)

Oct 28th, 2021 - The Centers for Disease Control and Prevention (CDC) recently updated its blood lead reference value (BLRV) from 5 µg/dL to 3.5 µg/dL in response to the Lead Exposure Prevention and Advisory Committee (LEPAC) recommendation made on May 14, 2021. The BLRV is intended to identify children with higher levels of lead in their blood compared to most children, based on the 97.5th percentile of the bl...

A Timeline of COVID-19 Vaccine Developments in 2021
https://www.ajmc.com/view/a-timeline-of-covid-19-vaccine-developments-in-2021
American Journal of Managed Care; AJMC Staff

Jun 3rd, 2021 - If 2020 was dominated by the news of how COVID-19 spread across the globe, then 2021 has so far been focused on ending the pandemic through vaccine distribution. Note: This timeline will update throughout the year as new developments take place.

Serious Mental Illness Diagnosis and COVID-19 Vaccine Uptake in the Veterans Health Adm...
https://doi.org/10.1176/appi.ps.202100499
Psychiatric Services (Washington, D.C.); Haderlein TP, Steers WN et. al.

Jan 20th, 2022 - This study examined the association between serious mental illness diagnoses and COVID-19 vaccination among Veterans Health Administration (VHA) patients. The sample (N=4,890,693) comprised veterans ages ≥18 years with VHA outpatient visits from March 1, 2018, through February 29, 2020. Veterans with serious mental illness were identified with ICD-10 diagnostic codes from electronic health reco...

Multiscale X-ray study of Bacillus subtilis biofilms reveals interlinked structural hie...
https://doi.org/10.1073/pnas.2118107119
Proceedings of the National Academy of Sciences of the Un... Azulay DN, Spaeker O et. al.

Jan 20th, 2022 - Biofilms are multicellular microbial communities that encase themselves in an extracellular matrix (ECM) of secreted biopolymers and attach to surfaces and interfaces. Bacterial biofilms are detrimental in hospital and industrial settings, but they can be beneficial, for example, in agricultural as well as in food technology contexts. An essential property of biofilms that grants them with incr...

Machine Learning Can be Used to Predict Function but Not Pain After Surgery for Thumb C...
https://doi.org/10.1097/CORR.0000000000002105
Clinical Orthopaedics and Related Research; Loos NL, Hoogendam L et. al.

Jan 20th, 2022 - Surgery for thumb carpometacarpal osteoarthritis is offered to patients who do not benefit from nonoperative treatment. Although surgery is generally successful in reducing symptoms, not all patients benefit. Predicting clinical improvement after surgery could provide decision support and enhance preoperative patient selection. This study aimed to develop and validate prediction models for clin...

Metabolic biomarkers related to cardiac dysfunction in metabolic-dysfunction-associated...
https://doi.org/10.1038/s41387-022-00182-7
Nutrition & Diabetes; Ismaiel A, Spinu M et. al.

Jan 20th, 2022 - Hepatic steatosis is associated with cardiac systolic and diastolic dysfunction. Therefore, we evaluated metabolites and their potential cardiovascular effects in metabolic-dysfunction-associated fatty liver disease (MAFLD). We conducted a cross-sectional study involving 75 participants (38 MAFLD and 37 controls). Hepatic steatosis was confirmed by hepatic ultrasonography and SteatoTestTM. Card...

Prognostic value, DNA variation and immunologic features of a tertiary lymphoid structu...
https://doi.org/10.1007/s00262-021-03123-y
Cancer Immunology, Immunotherapy : CII; Xu W, Ma C et. al.

Jan 20th, 2022 - The tumor microenvironment (TME) and tertiary lymphoid structures (TLS) affect the occurrence and development of cancers. How the immune contexture interacts with the phenotype of clear cell renal cell carcinoma (ccRCC) remains unclear. We identified and evaluated TLS clusters in ccRCC using machine learning algorithms and the 12-chemokine gene signature for TLS. Analyses for functional enrichm...

Management and outcome of prenatal absent pulmonary valve syndrome.
https://doi.org/10.1007/s00404-022-06397-4 10.1161/01.CIR.26.2.266 10.1007/s10554-015-0693-z 10.1053/j.semtcvs.2019.05.022 10.1002/pd.5094 10.1002/uog.15977 10.1016/j.athoracsur.2014.03.002 10.1002/uog.11193 10.1002/uog.2807 10.1002/uog.1729 10.1016/S0002-9149(02)03238-1 10.1046/j.1469-0705.2001.00242.x 10.1046/j.1540-8175.2002.00489.x 10.1016/S0002-9149(02)02326-3 10.1016/j.ejcts.2006.01.050
Archives of Gynecology and Obstetrics; Recker F, Weber EC et. al.

Jan 20th, 2022 - The purpose of this study was to explore the outcome in fetuses with prenatal diagnosis of absent pulmonary valve syndrome (APVS) on ultrasound imaging. A manual web scraping technique was utilized, where MEDLINE and EMBASE were searched along the combination with other relevant medical subject headings such as "absent pulmonary valve syndrome", "prenatal APVS" and "APVS/outcome". The observed ...

Blood copper excess is associated with mild cognitive impairment in elderly Chinese.
https://doi.org/10.1007/s40520-021-02034-3 10.1016/j.jalz.2010.11.002 10.1111/psyg.12723 10.1001/archneur.58.12.1985 10.1001/jama.2014.13806 10.1007/s11920-012-0291-x 10.1159/000357374 10.1016/j.jalz.2019.08.198 10.1007/s12011-020-02154-3 10.3389/fnagi.2021.630409 10.3390/biom11070960 10.1017/S1368980021001452 10.1186/s12877-021-02190-1 10.2174/1567205018666210324111401 10.3233/JAD-161033 10.1001/archneur.63.8.1085 10.3233/JAD-170552 10.1007/s00702-008-0080-1 10.1093/ajcn/81.4.822 10.3233/JAD-2012-111997 10.1016/j.jtemb.2012.04.012 10.3109/09638288809164105 10.1016/j.jclinepi.2006.06.008 10.3233/JAD-160119 10.1001/archneur.56.3.303 10.1007/s12011-016-0853-6 10.1016/j.jalz.2013.09.008 10.1016/j.jalz.2013.11.002 10.1111/psyg.12636 10.3233/JAD-2011-101821 10.3233/JAD-142655 10.1016/j.jalz.2011.12.009 10.1007/s12011-017-1042-y 10.1007/s12603-016-0759-1 10.1016/j.neuro.2013.12.001 10.3233/JAD-201556 10.1080/19336896.2021.1917289 10.4103/1673-5374.308076 10.1002/alz.12373 10.1007/s00775-009-0600-y 10.1073/pnas.1302212110 10.1016/0169-328X(91)90088-F 10.1016/S0896-6273(01)00317-8 10.1016/s0197-4580(02)00120-3 10.1016/j.jtemb.2012.04.019 10.3233/JAD-150601 10.3233/JAD-2010-100408 10.1016/j.brainresbull.2018.09.003 10.1021/acs.chemrestox.6b00373 10.3233/JAD-200483 10.1007/s00128-015-1611-8
Aging Clinical and Experimental Research; Gu L, Yu J et. al.

Jan 20th, 2022 - Copper is associated with mild cognitive impairment (MCI). However, there is a lack of relevant population studies with large sample sizes. This study used baseline data from a cohort study to determine the distribution characteristics of MCI in the elderly and to estimate the association between whole blood copper concentrations and MCI. MCI status was screened by the Mini-Mental State Examina...

Metals Contents in Honey, Beeswax and Bees and Human Health Risk Assessment Due to Cons...
https://doi.org/10.1007/s00244-021-00910-7
Archives of Environmental Contamination and Toxicology; Ullah R, Jan FA et. al.

Jan 20th, 2022 - Beeswax, honey, and live in-hive worker bees were collected in this study from eight districts in Khyber Pakhtunkhwa, Pakistan. The concentration of seven essential elements (copper, calcium, zinc, iron, nickel, chromium and manganese) and two non-essentials (lead and cadmium) were determined. All of the samples were found to have a random distribution of metal concentrations. The plentiful met...

Prognostic value of metabolic syndrome in renal structural changes in type 2 diabetes.
https://doi.org/10.1007/s11255-021-03051-x 10.1016/j.diabres.2019.107843 10.1016/j.diabres.2020.108078 10.1056/NEJMc1602469 10.1111/j.1464-5491.2004.01115.x 10.2215/CJN.02180311 10.3132/dvdr.2007.066 10.1371/journal.pone.0196332 10.1016/j.trsl.2017.03.002 10.1053/j.ajkd.2009.01.255 10.1152/ajprenal.00043.2013 10.7150/ijms.46259 10.1111/1753-0407.13150 10.4158/EP-2019-0512 10.1038/s41598-021-83856-z 10.1161/CIRCULATIONAHA.109.192644 10.1016/j.cca.2017.05.012 10.1016/S0140-6736(05)67402-8 10.1681/ASN.2010010010 10.1089/ham.2020.0076 10.1080/0886022x.2020.1804402 10.1155/2019/7825804 10.1038/srep20028 10.1016/j.jdiacomp.2015.12.002 10.1016/j.diabres.2019.04.022 10.1038/s41598-020-63967-9 10.1007/s00592-019-01324-7 10.1097/HJH.0000000000002129 10.1046/j.1523-1755.1998.00889.x 10.1038/nrneph.2009.184 10.2337/dc08-0971 10.1038/nrneph.2017.157 10.1007/s40620-015-0220-2 10.1053/j.ajkd.2008.02.004 10.1161/ATVBAHA.106.136325 10.1053/j.ajkd.2017.06.011 10.1038/nrneph.2015.180 10.1074/jbc.M116.730564 10.1038/ki.1997.387 10.1007/s12020-015-0587-9 10.1056/NEJMoa011489 10.1053/j.ajkd.2009.03.022
International Urology and Nephrology; Zhao L, Zou Y et. al.

Jan 20th, 2022 - To investigate the prognostic value of metabolic syndrome (MetS) and its relationship with renal structure changes in patients with type 2 diabetes and associated diabetic nephropathy (DN). 411 Chinese patients with type 2 diabetes and biopsy-confirmed DN were enrolled in this retrospective study. MetS was defined according to the modified criteria of the 2005 International Diabetes Federation....