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About 1,446,350 results

Predictors of early response to balloon pulmonary angioplasty in patients with inoperab...
https://doi.org/10.1177/17534666221138001
Therapeutic Advances in Respiratory Disease; Li X, Zhang Y et. al.

Nov 23rd, 2022 - To achieve favorable hemodynamics, the number of balloon pulmonary angioplasty (BPA) sessions varied significantly among patients with inoperable chronic thromboembolic pulmonary hypertension (CTEPH). Increased BPA sessions burdened patients financially and psychologically. We aim to identify baseline characteristics that could predict early BPA response. Consecutive patients who were diagnosed...

Role of radiomics in the diagnosis and treatment of gastrointestinal cancer.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669820
World Journal of Gastroenterology; Mao Q, Zhou MT et. al.

Nov 22nd, 2022 - Gastrointestinal cancer (GIC) has high morbidity and mortality as one of the main causes of cancer death. Preoperative risk stratification is critical to guide patient management, but traditional imaging studies have difficulty predicting its biological behavior. The emerging field of radiomics allows the conversion of potential pathophysiological information in existing medical images that can...

Novel management indications for conservative treatment of chylous ascites after gastri...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669821
World Journal of Gastroenterology; Kong PF, Xu YH et. al.

Nov 22nd, 2022 - Chylous ascites (CA) presents a challenge as a relatively common postoperative complication in gastric cancer (GC). Primary conservative therapy involved total parenteral nutrition, continuous low-pressure drainage, somatostatin, and a low-fat diet. Drainage tube (DT) clamping has been presented as a potential alternative conservative treatment for GC patients with CA. To propose novel conserva...

Esophageal lichen planus: Current knowledge, challenges and future perspectives.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669830
World Journal of Gastroenterology; Decker A, Schauer F et. al.

Nov 22nd, 2022 - Lichen planus (LP) is a frequent, chronic inflammatory disease involving the skin, mucous membranes and/or skin appendages. Esophageal involvement in lichen planus (ELP) is a clinically important albeit underdiagnosed inflammatory condition. This narrative review aims to give an overview of the current knowledge on ELP, its prevalence, pathogenesis, clinical manifestation, diagnostic criteria, ...

Effect of Singing on Symptoms in Stable COPD: A Systematic Review and Meta-Analysis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673938
International Journal of Chronic Obstructive Pulmonary Di... Fang X, Qiao Z et. al.

Nov 22nd, 2022 - Chronic obstructive pulmonary disease (COPD) is a chronic lung disease which feature is progressive airflow obstruction. Singing is a popular and convenient activity that requires people to manage their lung volumes and airflow actively. Despite the well-known benefits of singing to healthy people, the specific effect still remains unclear. To investigate the mental and psychological benefits o...

A Prospective Study of Pressure Injury Healing Rate and Time and Influencing Factors in...
https://doi.org/10.1097/01.ASW.0000892488.90282.a4
Advances in Skin & Wound Care; Seo Y, Oh H et. al.

Nov 22nd, 2022 - To determine pressure injury (PI) healing rate and time and identify influencing factors. A prospective cohort research design was used. Data collection was performed between May 2015 and August 2018. The study participants were 77 inpatients who developed at least one PI during their stay in a university hospital. Researchers assessed participants' demographic (age, sex); physical (incontinenc...

Pressure Injury Management in Critically Ill Patients with COVID-19 in a Makeshift Hosp...
https://doi.org/10.1097/01.ASW.0000891076.19171.39
Advances in Skin & Wound Care; Eveline K, Indirayani HW et. al.

Nov 22nd, 2022 - Patients who are critically ill with COVID-19 need ventilation support in the ICU. However, ICU patients are at higher risk of developing a pressure injury (PI). Unfortunately, PI prevention is not optimally implemented in Indonesia, especially in the makeshift hospitals created during the COVID-19 pandemic. Here, the authors report two cases of critically ill patients with COVID-19 who develop...

Fungating Malignancies: Management of a Distinct Wound Entity.
https://doi.org/10.1097/01.ASW.0000892972.45960.fa
Advances in Skin & Wound Care;

Nov 22nd, 2022 - Fungating Malignancies: Management of a Distinct Wound Entity.|2022||diagnosis,therapy,

A Lamin Family-Based Signature Predicts Prognosis and Immunotherapy Response in Hepatoc...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673181
Journal of Immunology Research; Yang Y, Xiao W et. al.

Nov 22nd, 2022 - Lamin family members play crucial roles in promoting oncogenesis and cancer development. The values of lamin family in predicting prognosis and immunotherapy response remain largely unclarified. Our research is aimed at comprehensively estimating the clinical significance of lamin family in hepatocellular carcinoma and constructing a novel lamin family-based signature to predict prognosis and g...

Strengthening the National Care System for Young Onset Dementia.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668884
International Journal of Public Health; Kogata T

Nov 22nd, 2022 - Strengthening the National Care System for Young Onset Dementia.|2022|Kogata T,|epidemiology,therapy,

Treatments to improve recovery after stroke.
https://doi.org/10.1177/17474930221136176
International Journal of Stroke : Official Journal of The...

Nov 22nd, 2022 - Treatments to improve recovery after stroke.|2022||therapy,

Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic b...
https://doi.org/10.1002/14651858.CD013551.pub2
The Cochrane Database of Systematic Reviews; Hayes K, Fernando MC et. al.

Nov 22nd, 2022 - Coagulopathy following cardiac surgery is associated with considerable blood product transfusion and high morbidity and mortality. The treatment of coagulopathy following cardiac surgery is challenging, with the replacement of clotting factors being based on transfusion of fresh frozen plasma (FFP). Prothrombin complex concentrate (PCCs) is an alternative method to replace clotting factors and ...

Facility-level program components leading to population impact: a coincidence analysis ...
https://doi.org/10.1093/tbm/ibac051
Translational Behavioral Medicine; Damschroder LJ, Miech EJ et. al.

Nov 22nd, 2022 - Obesity is a well-established risk factor for increased morbidity and mortality. Comprehensive lifestyle interventions, pharmacotherapy, and bariatric surgery are three effective treatment approaches for obesity. The Veterans Health Administration (VHA) offers all three domains but in different configurations across medical facilities. Study aim was to explore the relationship between configura...

An Electrophysiological Technique to Accurately Diagnose and Treat Erectile Dysfunction.
https://doi.org/10.3791/63851
Journal of Visualized Experiments : JoVE; Liu K, Wang Z et. al.

Nov 22nd, 2022 - Erectile dysfunction (ED) is a common disease in males. In the past, the first-line treatment of ED was mainly noninvasive-psychotherapy and oral phosphodiesterase 5 (PDE5) inhibitors. Oral PDE5 inhibitors often need to be used before sexual intercourse and do not repair the pathological damage; hence, the therapeutic effect for secondary ED caused by neurological or endocrine disorders is poor...

Azithromycin use prior to ICU admission is associated with a lower short-term mortality...
https://doi.org/10.1177/14799731221140797
Chronic Respiratory Disease; Guo X, Lin H et. al.

Nov 22nd, 2022 - Azithromycin was thought to prevent acute exacerbations of chronic obstructive pulmonary disease (AECOPDs) by anti-microbial and anti-inflammatory effects. However, it's value in the treatment of critically ill patients with AECOPD before ICU admission remains unclear. Our study aimed to find whether azithromycin use prior to ICU admission leads to better clinical outcomes for those individuals...

Clinicopathological characteristics and outcome predictors of anti-glomerular basement ...
https://doi.org/10.1080/0886022X.2022.2147673
Renal Failure; Ge Y, Liu K et. al.

Nov 22nd, 2022 - To explore the clinicopathological features of anti-glomerular basement membrane (anti-GBM) glomerulonephritis (anti-GBM-GN) and the prognostic values of clinical and laboratory indicators at diagnosis on renal and patient survival. A total of 76 patients (34 males and 42 females) with anti-GBM-GN who were hospitalized in the First Affiliated Hospital of Nanjing Medical University between Janua...

What Is in the Literature.
https://doi.org/10.1097/CND.0000000000000429
Journal of Clinical Neuromuscular Disease; Bromberg MB

Nov 22nd, 2022 - What is in the Literature focuses on chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), a neuropathy with challenges in diagnosis and treatment. A recent revision of diagnostic criteria (EFN/PNS criteria) has helped define clinical features of typical and atypical variants and what is not considered CIDP. Initiating pathologic factors is not known for typical CIDP or variants. Ne...

Health care workers' knowledge on identification, management and treatment of snakebite...
https://doi.org/10.1371/journal.pntd.0010841
PLoS Neglected Tropical Diseases; Aron MB, Kachimanga C et. al.

Nov 22nd, 2022 - Snakebite envenoming remains a public health threat in many African countries, including Malawi. However, there is a shortage of literature on the knowledge of Health Care Workers (HCWs) and the prevalence of snakebite cases in Malawi. We interviewed HCWs in Neno District to assess their knowledge of snake identification and management of snakebites. We further reviewed patient registers from 2...

Effect of exercise and/or educational interventions on physical activity and pain in pa...
https://doi.org/10.1371/journal.pone.0275591
PloS One; Sasaki R, Honda Y et. al.

Nov 22nd, 2022 - To investigate the effectiveness of exercise and/or educational intervention on physical activity and pain in patients with hip/knee osteoarthritis (OA) using systematic review and meta-analysis. We searched randomized controlled trials that investigated physical activity and pain and compared exercise and/or educational intervention with usual care in patients with hip/knee OA in MEDLINE (PubM...

Regulome analysis in B-acute lymphoblastic leukemia exposes Core Binding Factor addicti...
https://doi.org/10.1038/s41467-022-34653-3
Nature Communications; Wray JP, Deltcheva EM et. al.

Nov 22nd, 2022 - The ETV6-RUNX1 onco-fusion arises in utero, initiating a clinically silent pre-leukemic state associated with the development of pediatric B-acute lymphoblastic leukemia (B-ALL). We characterize the ETV6-RUNX1 regulome by integrating chromatin immunoprecipitation- and RNA-sequencing and show that ETV6-RUNX1 functions primarily through competition for RUNX1 binding sites and transcriptional repr...