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About 992,526 results

Effect of Bag-Mask Ventilation vs Endotracheal Intubation During Cardiopulmonary Resusc...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838565
JAMA Jabre P, Penaloza A et. al.

Feb 27th, 2018 - Bag-mask ventilation (BMV) is a less complex technique than endotracheal intubation (ETI) for airway management during the advanced cardiac life support phase of cardiopulmonary resuscitation of patients with out-of-hospital cardiorespiratory arrest. It has been reported as superior in terms of survival. To assess noninferiority of BMV vs ETI for advanced airway management with regard to surviv...

Effect of Loading Dose of Atorvastatin Prior to Planned Percutaneous Coronary Intervent...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876881
JAMA Berwanger O, Santucci EV et. al.

Mar 11th, 2018 - The effects of loading doses of statins on clinical outcomes in patients with acute coronary syndrome (ACS) and planned invasive management remain uncertain. To determine if periprocedural loading doses of atorvastatin decrease 30-day major adverse cardiovascular events (MACE) in patients with ACS and planned invasive management. Multicenter, double-blind, placebo-controlled, randomized clinica...

Improving Emergency Department Care for Pediatric Victims of Sexual Abuse.
https://doi.org/10.1542/peds.2018-1811
Pediatrics Hoehn EF, Overmann KM et. al.

Nov 10th, 2018 - Evidence-based medical care of sexual abuse victims who present to the pediatric emergency department (PED) is necessary to facilitate forensic evidence collection and prevent pregnancy and sexually transmitted infections. Adherence to testing and treatment guidelines remains low in PEDs, despite recommendations from the American Academy of Pediatrics and Centers for Disease Control and Prevent...

Risk of recurrence after a single manic or mixed episode - a systematic review and meta...
https://doi.org/10.1111/bdi.12593
Bipolar Disorders; Kessing LV, Andersen PK et. al.

Dec 14th, 2017 - For the first time to estimate the risk of recurrence among patients with a single manic/mixed episode by systematically reviewing prior studies on cohorts of adults, and cohorts of children and adolescents, respectively. A systematic literature search up to August 2017 was carried out including studies in which < 25% of the participants were estimated to have had a mood episode that required p...

Risk of suicide following an alcohol-related emergency hospital admission: An electroni...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922531
PloS One; Bowden B, John A et. al.

Apr 27th, 2018 - Alcohol misuse is a well-known risk factor for suicide however, the relationship between alcohol-related hospital admission and subsequent risk of death from suicide is unknown. We aimed to determine the risk of death from suicide following emergency admission to hospital with an alcohol-related cause. We established an electronic cohort study of all 2,803,457 residents of Wales, UK, aged from ...

Dual Antithrombotic Therapy with Dabigatran after PCI in Atrial Fibrillation.
https://doi.org/10.1056/NEJMoa1708454
The New England Journal of Medicine; Cannon CP, Bhatt DL et. al.

Aug 28th, 2017 - Triple antithrombotic therapy with warfarin plus two antiplatelet agents is the standard of care after percutaneous coronary intervention (PCI) for patients with atrial fibrillation, but this therapy is associated with a high risk of bleeding. In this multicenter trial, we randomly assigned 2725 patients with atrial fibrillation who had undergone PCI to triple therapy with warfarin plus a P2Y12...

Systematic review with meta-analysis: enteral nutrition therapy for the induction of re...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798240
Alimentary Pharmacology & Therapeutics; Swaminath A, Feathers A et. al.

Aug 17th, 2017 - Despite potential adverse-events in a paediatric population, corticosteroids are used to induce remission in paediatric Crohn's disease. Exclusive enteral nutrition also induces remission, but is infrequently used in the USA because corticosteroids are considered the superior therapy. New data have become available since the publication of the most recent meta-analysis in 2007. To see if curren...

Effect of Trans-Nasal Evaporative Intra-arrest Cooling on Functional Neurologic Outcome...
https://doi.org/10.1001/jama.2019.4149
JAMA Nordberg P, Taccone FS et. al.

May 7th, 2019 - Therapeutic hypothermia may increase survival with good neurologic outcome after cardiac arrest. Trans-nasal evaporative cooling is a method used to induce cooling, primarily of the brain, during cardiopulmonary resuscitation (ie, intra-arrest). To determine whether prehospital trans-nasal evaporative intra-arrest cooling improves survival with good neurologic outcome compared with cooling init...

Effect of Natriuretic Peptide-Guided Therapy on Hospitalization or Cardiovascular Morta...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605776
JAMA Felker GM, Anstrom KJ et. al.

Aug 22nd, 2017 - The natriuretic peptides are biochemical markers of heart failure (HF) severity and predictors of adverse outcomes. Smaller studies have evaluated adjusting HF therapy based on natriuretic peptide levels ("guided therapy") with inconsistent results. To determine whether an amino-terminal pro-B-type natriuretic peptide (NT-proBNP)-guided treatment strategy improves clinical outcomes vs usual car...

Consensus Recommendations for Evaluation, Interpretation, and Utilization of Computed T...
https://doi.org/10.1053/j.gastro.2017.11.274
Gastroenterology Bruining DH, Zimmermann EM et. al.

Jan 13th, 2018 - Computed tomography and magnetic resonance enterography have become routine small bowel imaging tests to evaluate patients with established or suspected Crohn's disease, but the interpretation and use of these imaging modalities can vary widely. A shared understanding of imaging findings, nomenclature, and utilization will improve the utility of these imaging techniques to guide treatment optio...

Effect of Dermatology Consultation on Outcomes for Patients With Presumed Cellulitis: A...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876891
JAMA Dermatology; Ko LN, Garza-Mayers AC et. al.

Feb 17th, 2018 - Each year, cellulitis leads to 650 000 hospital admissions and is estimated to cost $3.7 billion in the United States. Previous literature has demonstrated a high misdiagnosis rate for cellulitis, which results in unnecessary antibiotic use and health care cost. To determine whether dermatologic consultation decreases duration of hospital stay or intravenous antibiotic treatment duration in pat...

Outcomes of Early Dermatology Consultation for Inpatients Diagnosed With Cellulitis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876861
JAMA Dermatology; Li DG, Xia FD et. al.

Feb 17th, 2018 - Many inflammatory skin dermatoses mimic cellulitis (pseudocellulitis) and are treated with antibiotics and/or hospitalization, leading to unnecessary patient morbidity and substantial health care spending. To evaluate the impact of early dermatology consultation on clinical and economic outcomes associated with misdiagnosed cellulitis. This prospective cohort study enrolled patients with presum...

Screening for cognitive impairment in older adults: U.S. Preventive Services Task Force...
https://doi.org/10.7326/M14-0496
Annals of Internal Medicine; Moyer VA,

Mar 25th, 2014 - Update of the 2003 U.S. Preventive Services Task Force (USPSTF) recommendation on screening for dementia. The USPSTF reviewed the evidence on the benefits, harms, and sensitivity and specificity of screening instruments for cognitive impairment in older adults and the benefits and harms of commonly used treatment and management options for older adults with mild cognitive impairment or early de...

Fecal microbiota transplant for relapsing Clostridium difficile infection using a froze...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017893
Clinical Infectious Diseases : an Official Publication Of... Youngster I, Sauk J et. al.

Apr 25th, 2014 - Recurrent Clostridium difficile infection (CDI) with poor response to standard antimicrobial therapy is a growing medical concern. We aimed to investigate the outcomes of fecal microbiota transplant (FMT) for relapsing CDI using a frozen suspension from unrelated donors, comparing colonoscopic and nasogastric tube (NGT) administration. Healthy volunteer donors were screened and a frozen fecal s...

Management of gastrointestinal angiodysplastic lesions (GIADs): a systematic review and...
https://doi.org/10.1038/ajg.2014.19
The American Journal of Gastroenterology; Jackson CS, Gerson LB

Mar 19th, 2014 - Gastrointestinal angiodysplastic lesions (GIADs) are defined as pathologically dilated communications between veins and capillaries. The objective of this systematic review and meta-analysis was to determine the efficacy of available treatment modalities for GIADs. We identified eligible studies by searching through PubMed, SCOPUS, and Cochrane central register of controlled trials. We searched...

2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: exe...
https://doi.org/10.1161/CIR.0000000000000040
Circulation January CT, Wann LS et. al.

Mar 31st, 2014 - 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines and the Heart Rhythm Society.|2014|January CT,Wann LS,Alpert JS,Calkins H,Cigarroa JE,|standards,physiopathology,therapy,standards,standards,

The neuropsychiatry of tinnitus: a circuit-based approach to the causes and treatments ...
https://doi.org/10.1136/jnnp-2013-307339
Journal of Neurology, Neurosurgery, and Psychiatry; Minen MT, Camprodon J et. al.

Apr 19th, 2014 - Patients presenting with tinnitus commonly have neuropsychiatric symptoms with which physicians need to be familiar. We provide an overview of tinnitus, including its types and pathophysiology. We discuss how recent methods such as transcranial magnetic stimulation, positron emission tomography, MRI, magnetoencephalography and quantitative EEG improve our understanding of the pathophysiology of...

Withholding or termination of resuscitation in pediatric out-of-hospital traumatic card...
https://doi.org/10.1542/peds.2014-0176
Pediatrics , et. al.

Apr 1st, 2014 - This multiorganizational literature review was undertaken to provide an evidence base for determining whether recommendations for out-of-hospital termination of resuscitation could be made for children who are victims of traumatic cardiopulmonary arrest. Although there is increasing acceptance of out-of-hospital termination of resuscitation for adult traumatic cardiopulmonary arrest when there ...

Improving adherence to PALS septic shock guidelines.
https://doi.org/10.1542/peds.2013-3871
Pediatrics Paul R, Melendez E et. al.

Apr 8th, 2014 - Few studies have demonstrated improvement in adherence to Pediatric Advanced Life Support guidelines for severe sepsis and septic shock. We sought to improve adherence to national guidelines for children with septic shock in a pediatric emergency department with poor guideline adherence. Prospective cohort study of children presenting to a tertiary care pediatric emergency department with septi...

Randomised clinical trial: The beneficial effects of VSL#3 in obese children with non-a...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046270
Alimentary Pharmacology & Therapeutics; Alisi A, Bedogni G et. al.

Apr 17th, 2014 - Gut microbiota modifiers may have beneficial effects of non-alcoholic fatty liver disease (NAFLD) but randomised controlled trials (RCT) are lacking in children. To perform a double-blind RCT of VSL#3 vs. placebo in obese children with biopsy-proven NAFLD. Of 48 randomised children, 44 (22 VSL#3 and 22 placebo) completed the study. The main outcome was the change in fatty liver severity at 4 mo...