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About 89,395 results

Preventing disease transmission between people and wildlife.
https://doi.org/10.1038/d41586-022-03041-8
Nature Bendana C

Sep 28th, 2022 - Preventing disease transmission between people and wildlife.|2022|Bendana C,|transmission,prevention & control,transmission,

Using phylogenetics to infer HIV-1 transmission direction between known transmission pa...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499565
Proceedings of the National Academy of Sciences of the Un... Villabona-Arenas CJ, Hué S et. al.

Sep 15th, 2022 - Inferring the transmission direction between linked individuals living with HIV provides unparalleled power to understand the epidemiology that determines transmission. Phylogenetic ancestral-state reconstruction approaches infer the transmission direction by identifying the individual in whom the most recent common ancestor of the virus populations originated. While these methods vary in accur...

Reply to Wagman et al.: Data-driven assessments should establish the landscape of what ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499576
Proceedings of the National Academy of Sciences of the Un... Costantini C, Chandre F et. al.

Sep 13th, 2022 - Reply to Wagman et al.: Data-driven assessments should establish the landscape of what is "within reach" of malaria transmission control.|2022|Costantini C,Chandre F,Corbel V,Moiroux N,Simard F,|prevention & control,transmission,

Simulating respiratory disease transmission within and between classrooms to assess pan...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478679
Proceedings of the National Academy of Sciences of the Un... Endo 遠藤彰 A, et. al.

Sep 9th, 2022 - The global spread of coronavirus disease 2019 (COVID-19) has emphasized the need for evidence-based strategies for the safe operation of schools during pandemics that balance infection risk with the society's responsibility of allowing children to attend school. Due to limited empirical data, existing analyses assessing school-based interventions in pandemic situations often impose strong assum...

A single-administration therapeutic interfering particle reduces SARS-CoV-2 viral shedd...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522362
Proceedings of the National Academy of Sciences of the Un... Chaturvedi S, Beutler N et. al.

Sep 9th, 2022 - The high transmissibility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a primary driver of the COVID-19 pandemic. While existing interventions prevent severe disease, they exhibit mixed efficacy in preventing transmission, presumably due to their limited antiviral effects in the respiratory mucosa, whereas interventions targeting the sites of viral replication might more e...

Frequency of bystander exposure to antibiotics for enteropathogenic bacteria among youn...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457395
Proceedings of the National Academy of Sciences of the Un... Rogawski McQuade ET, Brennhofer SA et. al.

Aug 30th, 2022 - Children in low-resource settings carry enteric pathogens asymptomatically and are frequently treated with antibiotics, resulting in opportunities for pathogens to be exposed to antibiotics when not the target of treatment (i.e., bystander exposure). We quantified the frequency of bystander antibiotic exposures for enteric pathogens and estimated associations with resistance among children in e...

Reply to Klein et al.: The importance of aerosol pH for airborne respiratory virus tran...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522416
Proceedings of the National Academy of Sciences of the Un... Oswin HP, Haddrell AE et. al.

Aug 30th, 2022 - Reply to Klein et al.: The importance of aerosol pH for airborne respiratory virus transmission.|2022|Oswin HP,Haddrell AE,Otero-Fernandez M,Mann JFS,Cogan TA,|virology,transmission,virology,transmission,

Wildlife susceptibility to infectious diseases at global scales.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436312
Proceedings of the National Academy of Sciences of the Un... Robles-Fernández ÁL, Santiago-Alarcon D et. al.

Aug 23rd, 2022 - Disease transmission prediction across wildlife is crucial for risk assessment of emerging infectious diseases. Susceptibility of host species to pathogens is influenced by the geographic, environmental, and phylogenetic context of the specific system under study. We used machine learning to analyze how such variables influence pathogen incidence for multihost pathogen assemblages, including on...

Human behaviour, NPI and mobility reduction effects on COVID-19 transmission in differe...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9394048
BMC Public Health; Mohammadi Z, Cojocaru MG et. al.

Aug 23rd, 2022 - The outbreak of Coronavirus disease, which originated in Wuhan, China in 2019, has affected the lives of billions of people globally. Throughout 2020, the reproduction number of COVID-19 was widely used by decision-makers to explain their strategies to control the pandemic. In this work, we deduce and analyze both initial and effective reproduction numbers for 12 diverse world regions between F...

Epidemiological, virological and serological investigation of a SARS-CoV-2 outbreak (Al...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385020
PloS One; Lorthe E, Bellon M et. al.

Aug 18th, 2022 - To report a prospective epidemiological, virological and serological investigation of a SARS-CoV-2 outbreak in a primary school. As part of a longitudinal, prospective, school-based surveillance study, this investigation involved repeated testing of 73 pupils, 9 teachers, 13 non-teaching staff and 26 household members of participants who tested positive, with rapid antigen tests and/or RT-PCR (...

Identification of basal complex protein that is essential for maturation of transmissio...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407223
Proceedings of the National Academy of Sciences of the Un... Clements RL, Morano AA et. al.

Aug 17th, 2022 - Malaria remains a global driver of morbidity and mortality. To generate new antimalarials, one must elucidate the fundamental cell biology of Plasmodium falciparum, the parasite responsible for the deadliest cases of malaria. A membranous and proteinaceous scaffold called the inner membrane complex (IMC) supports the parasite during morphological changes, including segmentation of daughter cell...

The effectiveness of COVID-19 testing and contact tracing in a US city.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407477
Proceedings of the National Academy of Sciences of the Un... Wang X, Du Z et. al.

Aug 16th, 2022 - Although testing, contact tracing, and case isolation programs can mitigate COVID-19 transmission and allow the relaxation of social distancing measures, few countries worldwide have succeeded in scaling such efforts to levels that suppress spread. The efficacy of test-trace-isolate likely depends on the speed and extent of follow-up and the prevalence of SARS-CoV-2 in the community. Here, we u...

The Emergence, Diversification, and Transmission of Subgroup J Avian Leukosis Virus Rev...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472763
Journal of Virology; Deng Q, Li Q et. al.

Aug 12th, 2022 - The geographical spread and inter-host transmission of the subgroup J avian leukosis virus (ALV-J) may be the most important issues for epidemiology. An integrated analysis, including phylogenetic trees, homology modeling, evolutionary dynamics, selection analysis and viral transmission, based on the gp85 gene sequences of the 665 worldwide ALV-J isolates during 1988-2020, was performed. A new ...

Geographic patterns of koala retrovirus genetic diversity, endogenization, and subtype ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388103
Proceedings of the National Academy of Sciences of the Un... Blyton MDJ, Young PR et. al.

Aug 10th, 2022 - Koala retrovirus (KoRV) subtype A (KoRV-A) is currently in transition from exogenous virus to endogenous viral element, providing an ideal system to elucidate retroviral-host coevolution. We characterized KoRV geography using fecal DNA from 192 samples across 20 populations throughout the koala's range. We reveal an abrupt change in KoRV genetics and incidence at the Victoria/New South Wales st...

Assessing suspension and infectivity times of virus-loaded aerosols involved in airborn...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371747
Proceedings of the National Academy of Sciences of the Un... Merhi T, Atasi O et. al.

Aug 6th, 2022 - Airborne transmission occurs through droplet-mediated transport of viruses following the expulsion of an aerosol by an infected host. Transmission efficiency results from the interplay between virus survival in the drying droplet and droplet suspension time in the air, controlled by the coupling between water evaporation and droplet sedimentation. Furthermore, droplets are made of a respiratory...

Animal Reservoirs-Where the Next SARS-CoV-2 Variant Could Arise.
https://doi.org/10.1001/jama.2022.9789
JAMA Madhusoodanan J

Aug 4th, 2022 - Animal Reservoirs-Where the Next SARS-CoV-2 Variant Could Arise.|2022|Madhusoodanan J,|genetics,transmission,virology,virology,virology,genetics,

Risk of severe COVID-19 infection among adults with prior exposure to children.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388132
Proceedings of the National Academy of Sciences of the Un... Solomon MD, Escobar GJ et. al.

Jul 28th, 2022 - Susceptibility and severity of COVID-19 infection vary widely. Prior exposure to endemic coronaviruses, common in young children, may protect against SARS-CoV-2. We evaluated risk of severe COVID-19 among adults with and without exposure to young children in a large, integrated healthcare system. Adults with children 0-5 years were matched 1:1 to adults with children 6-11 years, 12-18 years, an...

Evaluating the efficacy of the HITSystem 2.1 to improve PMTCT retention and maternal vi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321364
PloS One; Mokua S, Maloba M et. al.

Jul 27th, 2022 - Gaps in the provision of guideline-adherent prevention of mother-to-child transmission of HIV (PMTCT) services and maternal retention in care contribute to nearly 8000 Kenyan infants becoming infected with HIV annually. Interventions that routinize evidence-based PMTCT service delivery and foster consistent patient engagement are essential to eliminating mother-to-child transmission of HIV. The...

How long is COVID infectious? What scientists know so far.
https://doi.org/10.1038/d41586-022-02026-x
Nature Adam D

Jul 27th, 2022 - How long is COVID infectious? What scientists know so far.|2022|Adam D,|transmission,virology,transmission,virology,growth & development,pathogenicity,

Mouse Scarb2 Modulates EV-A71 Pathogenicity in Neonatal Mice.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364792
Journal of Virology; Miwatashi W, Ishida M et. al.

Jul 23rd, 2022 - Enterovirus A71 (EV-A71) is a human pathogen that causes hand, foot, and mouth disease, which can progress to severe neurological disease. EV-A71 infects humans via the human scavenger receptor B2 (hSCARB2). It can also infect neonatal mice experimentally. Wild-type (WT) EV-A71 strains replicate primarily in the muscle of neonatal mice; however, susceptibility lasts only for a week after birth....