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About 229,608 results

Opioid Knowledge and Prescribing Practices Among Obstetrician-Gynecologists.
https://doi.org/10.1097/AOG.0000000000002407
Obstetrics and Gynecology; Madsen AM, Stark LM et. al.

Dec 7th, 2017 - To describe obstetrician-gynecologists' (ob-gyns) knowledge and prescribing practices regarding opioid analgesics. We conducted a cross-sectional survey of a national sample of American College of Obstetricians and Gynecologists Fellows and Junior Fellows who are part of the Collaborative Ambulatory Research Network. We used a sequential mixed-method approach. We collected data on opioid knowle...

Outcomes With Transcatheter Mitral Valve Repair in the United States: An STS/ACC TVT Re...
https://doi.org/10.1016/j.jacc.2017.09.015
Journal of the American College of Cardiology; Sorajja P, Vemulapalli S et. al.

Nov 3rd, 2017 - Post-market surveillance is needed to evaluate the real-world clinical effectiveness and safety of U.S. Food and Drug Administration-approved devices. The authors examined the commercial experience with transcatheter mitral valve repair for the treatment of mitral regurgitation. Data from the Society of Thoracic Surgery/American College of Cardiology Transcatheter Valve Therapy Registry on pati...

Vital Signs: Trends in Emergency Department Visits for Suspected Opioid Overdoses - Uni...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844282
MMWR. Morbidity and Mortality Weekly Report; Vivolo-Kantor AM, Seth P et. al.

Mar 8th, 2018 - From 2015 to 2016, opioid overdose deaths increased 27.7%, indicating a worsening of the opioid overdose epidemic and highlighting the importance of rapid data collection, analysis, and dissemination. Emergency department (ED) syndromic and hospital billing data on opioid-involved overdoses during July 2016-September 2017 were examined. Temporal trends in opioid overdoses from 52 jurisdictions ...

A critical appraisal of neuroimaging studies of bipolar disorder: toward a new conceptu...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119497
The American Journal of Psychiatry; Phillips ML, Swartz HA

Mar 14th, 2014 - In this critical review, the authors appraise neuroimaging findings in bipolar disorder in emotion-processing, emotion-regulation, and reward-processing neural circuitry in order to synthesize the current knowledge of the neural underpinnings of bipolar disorder and provide a neuroimaging research road map for future studies. The authors examined findings from all major studies in bipolar disor...

Circumcision rates in the United States: rising or falling? What effect might the new a...
https://doi.org/10.1016/j.mayocp.2014.01.001
Mayo Clinic Proceedings; Morris BJ, Bailis SA et. al.

Apr 7th, 2014 - The objective of this review was to assess the trend in the US male circumcision rate and the impact that the affirmative 2012 American Academy of Pediatrics policy statement might have on neonatal circumcision practice. We searched PubMed for the term circumcision to retrieve relevant articles. This review was prompted by a recent report by the Centers for Disease Control and Prevention that f...

Long-term outcomes of patients with nonsurgically managed uncomplicated appendicitis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151128
Journal of the American College of Surgeons; McCutcheon BA, Chang DC et. al.

Mar 25th, 2014 - Emerging literature has supported the safety of nonoperative management of uncomplicated appendicitis. Patients with emergent, uncomplicated appendicitis were identified by appropriate ICD-9 diagnosis codes in the California Office of Statewide Health Planning and Development database from 1997 to 2008. Rates of treatment failure, recurrence, and perforation after nonsurgical management were ca...

The changing face of heroin use in the United States: a retrospective analysis of the p...
https://doi.org/10.1001/jamapsychiatry.2014.366
JAMA Psychiatry; Cicero TJ, Ellis MS et. al.

May 29th, 2014 - Over the past several years, there have been a number of mainstream media reports that the abuse of heroin has migrated from low-income urban areas with large minority populations to more affluent suburban and rural areas with primarily white populations. To examine the veracity of these anecdotal reports and define the relationship between the abuse of prescription opioids and the abuse of her...

Long-term survival following coronary artery bypass grafting: off-pump versus on-pump s...
https://doi.org/10.1016/j.jacc.2014.02.584
Journal of the American College of Cardiology; Kim JB, Yun SC et. al.

Apr 7th, 2014 - This study sought to compare long-term survival after off- and on-pump coronary artery bypass grafting (CABG). Although several large-scale clinical trials have compared the surgical outcomes between off- and on-pump CABG, the long-term survival has not been compared between the 2 surgical strategies in a reasonably sized cohort. We evaluated long-term survival data in 5,203 patients (age 62.9 ...

Increased 1-year healthcare use in survivors of severe sepsis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226030
American Journal of Respiratory and Critical Care Medicine; Prescott HC, Langa KM et. al.

May 29th, 2014 - Hospitalizations for severe sepsis are common, and a growing number of patients survive to hospital discharge. Nonetheless, little is known about survivors' post-discharge healthcare use. To measure inpatient healthcare use of severe sepsis survivors compared with patients' own presepsis resource use and the resource use of survivors of otherwise similar nonsepsis hospitalizations. This is an o...

Stroke incidence and mortality trends in US communities, 1987 to 2011.
https://doi.org/10.1001/jama.2014.7692
JAMA Koton S, Schneider AL et. al.

Jul 16th, 2014 - Prior studies have shown decreases in stroke mortality over time, but data on validated stroke incidence and long-term trends by race are limited. To study trends in stroke incidence and subsequent mortality among black and white adults in the Atherosclerosis Risk in Communities (ARIC) cohort from 1987 to 2011. Prospective cohort study of 14,357 participants (282,097 person-years) free of strok...

Prognostic value of fasting versus nonfasting low-density lipoprotein cholesterol level...
https://doi.org/10.1161/CIRCULATIONAHA.114.010001
Circulation Doran B, Guo Y et. al.

Jul 12th, 2014 - National and international guidelines recommend fasting lipid panel measurement for risk stratification of patients for prevention of cardiovascular events. However, the prognostic value of fasting versus nonfasting low-density lipoprotein cholesterol (LDL-C) is uncertain. Patients enrolled in the National Health and Nutrition Examination Survey III (NHANES-III), a nationally representative cro...

Trends in hospitalizations and outcomes for acute cardiovascular disease and stroke, 19...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171056
Circulation Krumholz HM, Normand SL et. al.

Aug 19th, 2014 - During the past decade, efforts focused intensely on improving the quality of care for people with, or at risk for, cardiovascular disease and stroke. We sought to quantify the changes in hospitalization rates and outcomes during this period. We used national Medicare data to identify all Fee-for-Service patients ≥65 years of age who were hospitalized with unstable angina, myocardial infarction...

What is the optimal chest compression depth during out-of-hospital cardiac arrest resus...
https://doi.org/10.1161/CIRCULATIONAHA.114.008671
Circulation Stiell IG, Brown SP et. al.

Sep 25th, 2014 - The 2010 American Heart Association guidelines suggested an increase in cardiopulmonary resuscitation compression depth with a target >50 mm and no upper limit. This target is based on limited evidence, and we sought to determine the optimal compression depth range. We studied emergency medical services-treated out-of-hospital cardiac arrest patients from the Resuscitation Outcomes Consortium P...

Seasonal variation of relapse rate in multiple sclerosis is latitude dependent.
https://doi.org/10.1002/ana.24287
Annals of Neurology; Spelman T, Gray O et. al.

Oct 6th, 2014 - Previous studies assessing seasonal variation of relapse onset in multiple sclerosis have had conflicting results. Small relapse numbers, differing diagnostic criteria, and single region studies limit the generalizability of prior results. The aim of this study was to determine whether there is a temporal variation in onset of relapses in both hemispheres and to determine whether seasonal peak ...

Young adult psychological outcome after puberty suppression and gender reassignment.
https://doi.org/10.1542/peds.2013-2958
Pediatrics de Vries AL, McGuire JK et. al.

Sep 9th, 2014 - In recent years, puberty suppression by means of gonadotropin-releasing hormone analogs has become accepted in clinical management of adolescents who have gender dysphoria (GD). The current study is the first longer-term longitudinal evaluation of the effectiveness of this approach. A total of 55 young transgender adults (22 transwomen and 33 transmen) who had received puberty suppression durin...

Increased mortality associated with digoxin in contemporary patients with atrial fibril...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405246
Journal of the American College of Cardiology; Turakhia MP, Santangeli P et. al.

Aug 15th, 2014 - Despite endorsement of digoxin in clinical practice guidelines, there exist limited data on its safety in atrial fibrillation/flutter (AF). The goal of this study was to evaluate the association of digoxin with mortality in AF. Using complete data of the TREAT-AF (The Retrospective Evaluation and Assessment of Therapies in AF) study from the U.S. Department of Veterans Affairs (VA) healthcare s...

Association of STOP-Bang Questionnaire as a Screening Tool for Sleep Apnea and Postoper...
https://doi.org/10.1213/ANE.0000000000002344
Anesthesia and Analgesia; Nagappa M, Patra J et. al.

Aug 17th, 2017 - The risk of postoperative complications increases with undiagnosed obstructive sleep apnea (OSA). The high-risk OSA (HR-OSA) patients can be easily identified using the STOP-Bang screening tool. The aim of this systematic review and meta-analysis is to determine the association of postoperative complications in patients screened as HR-OSA versus low-risk OSA (LR-OSA). The following data bases w...

Longitudinal recovery patterns of penile length and the underexplored benefit of long-t...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941788
BMC Urology; Kwon YS, Farber N et. al.

May 9th, 2018 - Penile length (PL) shortening is an underreported phenomenon following radical prostatectomy (RP) and risk factors are not fully explored. We aimed to describe longitudinal patterns of PL recovery and evaluate factors predicting complete return to baseline PL. PL measurement was performed during a preoperative and postoperative follow-up visits at 7 days and 3, 6, 9, and 12 months. Patients who...

ILAE official report: a practical clinical definition of epilepsy.
https://doi.org/10.1111/epi.12550
Epilepsia Fisher RS, Acevedo C et. al.

Apr 15th, 2014 - Epilepsy was defined conceptually in 2005 as a disorder of the brain characterized by an enduring predisposition to generate epileptic seizures. This definition is usually practically applied as having two unprovoked seizures >24 h apart. The International League Against Epilepsy (ILAE) accepted recommendations of a task force altering the practical definition for special circumstances that do ...

Vorapaxar in patients with diabetes mellitus and previous myocardial infarction: findin...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365950
Circulation Cavender MA, Scirica BM et. al.

Feb 14th, 2015 - Vorapaxar reduces cardiovascular death, myocardial infarction (MI), or stroke in patients with previous MI while increasing bleeding. Patients with diabetes mellitus (DM) are at high risk of recurrent thrombotic events despite standard therapy and may derive particular benefit from antithrombotic therapies. The Thrombin Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Ev...