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About 64,603 results

Urinary single-cell transcriptomics: a promising noninvasive method for assessing acute...
https://doi.org/10.1016/j.kint.2022.09.006
Kidney International; Hasegawa S

Nov 22nd, 2022 - Noninvasive methods for obtaining intrarenal information are required to understand the mechanism of acute kidney injury (AKI). Klocke et al. explored the feasibility of using urinary single-cell RNA sequencing in assessing human AKI. Urine samples from patients with AKI included tubular epithelial cells with injury-related dedifferentiation and adaptive phenotypes, which could reflect kidney t...

Identification and validation of methylated PENK gene for early detection of bladder ca...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675278
BMC Cancer; Oh TJ, Lim E et. al.

Nov 20th, 2022 - Early detection of bladder cancer (BCa) offers patients a favorable outcome and avoids the need for cystectomy. Development of an accurate and sensitive noninvasive BCa diagnostic test is imperative. DNA methylation is an early epigenetic event in the development of BCa. Certain specific aberrant methylations could serve as useful biomarkers. The aim of this study was to identify methylation bi...

Relationship between Blood Lipid Profiles and Risk of Lupus Nephritis in Children.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629941
International Journal of Clinical Practice; Liu J, Song W et. al.

Nov 10th, 2022 - Systemic lupus erythematosus (SLE) is a relatively common rheumatic disease in children. The characteristics of blood lipid metabolism in children with LN are little reported. This study aimed to explore the relationship between blood lipid profiles and the risk of lupus nephritis (LN) in children. A total of 134 children with newly diagnosed SLE were divided into LN and non-LN groups according...

Anxiety and depression symptoms, albuminuria and risk of acute myocardial infarction in...
https://doi.org/10.1186/s12872-022-02921-1
BMC Cardiovascular Disorders; Gustad LT, Myklebust TÅ et. al.

Nov 10th, 2022 - Studies suggest increased risk for an outcome in people with joint exposures that share common causal pathways. The objective of this study was to determine the risk of incident acute myocardial infarction (AMI) following exposure to both albuminuria and/or anxiety and depression symptoms. Participants who provided urine samples to the HUNT2 (1995-97) or HUNT3 (2007-2009) surveys were followed ...

Phenol and Phthalate Effects on Thyroid Hormone Levels during Pregnancy: Relying on In ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645207
Environmental Health Perspectives; Nakiwala D, Noyes PD et. al.

Nov 10th, 2022 - Studies characterizing associations between phenols, phthalates and thyroid hormones during pregnancy produce inconsistent results. This divergence may be partly attributable to false positives due to multiple comparison testing of large numbers of chemicals, and measurement error as studies rely on small numbers of biospecimens despite high intra-individual variability in urinary chemical meta...

Using hyrax latrines to investigate climate change.
https://doi.org/10.1038/d41586-022-03587-7
Nature Jones N

Nov 8th, 2022 - Using hyrax latrines to investigate climate change.|2022|Jones N,|statistics & numerical data,urine,chemistry,

Assessment of early kidney injury caused by asymptomatic bacteriuria in children with t...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9639256
BMC Pediatrics; Bebars GM, Mostafa AN et. al.

Nov 8th, 2022 - Infection is one of the most frequent causes of morbidity and mortality in diabetic patients. Some microorganisms become more virulent in a high glucose concentration. Diabetics are more likely to have asymptomatic and symptomatic bacteriuria. NGAL is secreted in high concentrations into the blood and urine within two hours of AKI. The aim of the study is early detection of UTI in type1diabetic...

Behaviors of Water Intake, Hydration Status, and Related Hydration Biomarkers among Phy...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592216
International Journal of Clinical Practice; Zhang N, Zhang J et. al.

Nov 3rd, 2022 - Studies on the water intake of athletes in daily life are insufficient. The objective was to determine the water intake and hydration status among physically active male young adults. In this cross-sectional studies study, 111 physically active male young adults were recruited. The amount of daily total drinking fluid intake (TDF) among participants was recorded and evaluated in real time over ...

Long-term exposure to low concentrations of polycyclic aromatic hydrocarbons and altera...
https://doi.org/10.1371/journal.pone.0276944
PloS One; Cui J, Zhang T et. al.

Nov 3rd, 2022 - Long-term exposure to low polycyclic aromatic hydrocarbon (PAH) concentration may ave detrimental effects, including changing platelet indices. Effects of chronic exposure to low PAH concentrations have been evaluated in cross-sectional, but not in longitudinal studies, to date. We aimed to assess the effects of long-term exposure to the low-concentration PAHs on alterations in platelet indices...

Association of urinary bisphenol A concentrations with in vitro fertilisation outcomes:...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9628666
BMJ Open; Cao XL, Xu NX et. al.

Nov 2nd, 2022 - Bisphenol A (BPA) is a common environmental endocrine disruptor. BPA has been reported to be associated with female infertility, which may not only affect natural pregnancy and natural fertility but also affect the outcomes of in vitro fertilisation (IVF). BPA exposure may help to partly explain the unsatisfactory IVF outcomes, but the relationship between the concentrations of BPA in urine and...

Nuclear Magnetic Resonance Metabolomic Profiling and Urine Chemistries in Incident Kidn...
https://doi.org/10.1681/ASN.2022040416
Journal of the American Society of Nephrology : JASN; Thongprayoon C, Vuckovic I et. al.

Nov 1st, 2022 - The urine metabolites and chemistries that contribute to kidney stone formation are not fully understood. This study examined differences between the urine metabolic and chemistries profiles of first-time stone formers and controls. High-resolution 1H-nuclear magnetic resonance (NMR) spectroscopy-based metabolomic analysis was performed in 24-hour urine samples from a prospective coh...

Progression of Chronic Kidney Disease Risk Categories and Risk of Cardiovascular Diseas...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673645
Journal of the American Heart Association; Choi Y, Jacobs DR et. al.

Nov 1st, 2022 - Background Previous studies of worsening chronic kidney disease (CKD) based on declining estimated glomerular filtration rate (eGFR) or increasing urine albumin-creatinine ratio (UACR) are limited to later middle-age and older adults. We examined associations of CKD progression and incident cardiovascular disease (CVD) and mortality in younger adults. Methods and Results We studied 4382 adults ...

Passive smoking and urinary oxidative biomarkers: A pilot study of healthy travelers fr...
https://doi.org/10.1016/j.ijheh.2022.114048
International Journal of Hygiene and Environmental Health; Lin Y, Zhu Y et. al.

Oct 30th, 2022 - There is a great heterogeneity in smoking prevalence and tobacco control policy across different countries. However, it is unknown whether this heterogeneity could cause increased passive smoking and adverse health effects among international travelers. In this pilot study, we collected 190 urine samples from 26 Los Angeles residents before (LA-before), during (Beijing), and after (LA-after) a ...

Urinary RBP as an Independent Predictor of Renal Outcome in Diabetic Nephropathy.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592234
Disease Markers; Cai F, Zhang L et. al.

Oct 28th, 2022 - Renal tubular impairment is prevalent in diabetic nephropathy (DN) and the histological severity predicted renal outcome. Biomarkers of tubular injury also increased in the urine of DN patients. The retrospective study aimed to assess the prognostic value of clinically widely applied urinary tubular injury markers, retinol-binding protein (RBP), β2-microglobulin (β2-MG) and N-acetyl-β-D-glucosa...

Luminophore Chemistry for Detection of Urinary Bladder Cancer - Comparison to Cytology ...
https://doi.org/10.21873/anticanres.16031
Anticancer Research; Ecke TH, Scislowski M et. al.

Oct 27th, 2022 - New luminometric chelates were developed for the detection of urinary bladder cancer and compared to cytology and urinary rapid tests BTA stat®, NMP22® BladderChek® and UBC® Rapid Test. This single-center study analyzed urine from two different cohorts: Firstly, a retrospective pilot cohort (n=27) and secondly a prospective validation cohort (n=60) including patients with bladder cancer and hea...

Is there a relationship between 24-hour urinary sodium and potassium and mental health ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592346
Medicine Arab A, Zabibah RS et. al.

Oct 26th, 2022 - There is a lack of evidence and consensus in terms of the association between dietary intake of sodium (Na) and potassium (K) with mental health. By using 24-hours urinary samples as the gold standard method, we conducted a study to explore the association between dietary intake of Na and K with parameters of mental health including depression, anxiety, and stress among an Iranian population di...

Higher proportion of agricultural land use around the residence is associated with high...
https://doi.org/10.1016/j.ijheh.2022.114039
International Journal of Hygiene and Environmental Health; De Troeyer K, Casas L et. al.

Oct 25th, 2022 - Pesticides, including herbicides, are widely used for agricultural and sanitary reasons and concerns have been raised about their various health effects. Little research has been done into the extent to which agricultural land use in the residential surroundings contributes to (internal) exposure of pesticides. We investigated the associations between the proportion of agricultural land use aro...

Cadmium exposure in adults across Europe: Results from the HBM4EU Aligned Studies surve...
https://doi.org/10.1016/j.ijheh.2022.114050
International Journal of Hygiene and Environmental Health; Snoj Tratnik J, Kocman D et. al.

Oct 21st, 2022 - The objectives of the study were to estimate the current exposure to cadmium (Cd) in Europe, potential differences between the countries and geographic regions, determinants of exposure and to derive European exposure levels. The basis for this work was provided by the European Human Biomonitoring Initiative (HBM4EU) which established a framework for alignment of national or regional HBM studie...

Update: Correlation of Fentanyl Positive Drug Screens with other Medications in Patient...
https://www.ncbi.nlm.nih.gov/pubmed/36261190
Annals of Clinical and Laboratory Science; Pesce A, Tran K et. al.

Oct 20th, 2022 - To monitor fentanyl polydrug use over past six years. Calculate percent of fentanyl and other drugs positive in urine drug tests. Percent of fentanyl positive drug tests remained unchanged, but increases in fentanyl/methamphetamine and fentanyl/marijuana were observed. Fentanyl laced illicit drugs remain a major substance abuse problem.

Glomerular filtration rate by different measures and albuminuria are associated with ri...
https://doi.org/10.1007/s40520-022-02245-2
Aging Clinical and Experimental Research; Zhang H, Hao M et. al.

Oct 20th, 2022 - A decreased estimated glomerular filtration rate (eGFR) is associated with frailty, but the association between kidney function and frailty using multidimensional assessments has not been entirely examined. We aimed to investigate whether albuminuria and the eGFR using different biomarkers were associated with frailty. A total of 1830 older adults were included. Kidney function was assessed by ...