ALLMEDx | COVID Organ Dysfunction

Comorbidities and multi-organ injuries in the treatment of COVID-19
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30558-4/fulltext

More attention should be paid to comorbidities in the treatment of COVID-19. In the literature, COVID-19 is characterised by the symptoms of viral pneumonia such as fever, fatigue, dry cough, and lymphopenia. Many of the older patients who become severely ill have evidence of underlying illness such as cardiovascular disease, liver disease, kidney disease, or maligna...

Post-covid syndrome in individuals admitted to hospital with covid-19: retrospective cohort study
https://www.bmj.com/content/372/bmj.n693
BMJ Ayoubkhani D, Khunti K et. al.

Mar 31st, 2021 - Objective To quantify rates of organ specific dysfunction in individuals with covid-19 after discharge from hospital compared with a matched control group from the general population.

Megakaryocytes and platelet-fibrin thrombi characterize multi-organ thrombosis at autopsy in COVID-19: A case series
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(20)30178-4/fulltext

There is increasing recognition of a prothrombotic state in COVID-19. Post-mortem examination can provide important mechanistic insights.

Joint Statement about COVID-19 Vaccination in Organ Transplant Candidates and Recipients
https://www.myast.org/joint-statement-about-covid-19-vaccination-organ-transplant-candidates-and-recipients
American Study of Transplantation;

Jan 5th, 2022 - AST, ASTS, and ISHLT published a joint statement on COVID-19 vaccines with the latest detail about vaccinations in organ transplant candidates and recipients, including the latest references, details on booster and additional doses of mRNA vaccines, and updated recommendations pre- and post-transplantation.

COVID-19 High - COVID-19 in Vietnam
https://tools.cdc.gov/medialibrary/index.aspx#/media/id/428062

Make sure you are vaccinated and up to date with your COVID-19 vaccines before traveling to Vietnam. If you are not up to date with COVID-19 vaccines, avoid travel to Vietnam.

COVID-19 and the Forgotten Organ: Prolonged Changes to the Metabol...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596650
Gastroenterology Venzon M, Cadwell K

Nov 21st, 2021 - COVID-19 and the Forgotten Organ: Prolonged Changes to the Metabolic Output of the Gut Microbiome.|2021|Venzon M,Cadwell K,|

The mechanism of multiple organ dysfunction syndrome in patients with ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015222
Journal of Medical Virology; Zhao W, Li H et. al.

Jan 29th, 2022 - In late 2019, an outbreak of coronavirus disease 2019 (COVID-19) arose, caused by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2). This disease rapidly became a public health event of international concern. In addition to the most typical symptoms of dyspnea, numerous patients with COVID-19 exhibited systemic symptoms, such as cardiova...

The clinical characters and prognosis of COVID-19 patients with multiple ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519259
Medicine Cui J, Yuan B et. al.

Nov 4th, 2021 - To depict the clinical characters and prognosis of coronavirus disease 2019 patients who developed multiple organ dysfunction syndrome (MODS).A cohort consisted of 526 patients, which including 109 patients complicated MODS, was retrospectively analyzed to examine the clinical characteristics and risk factors of MODS.Among the 526 novel coronavirus-infected pneumonia patients, 109...

Endothelial dysfunction in COVID-19: A potential predictor of long...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8610828
International Journal of Cardiology; Seitz A, Ong P

Nov 29th, 2021 - Endothelial dysfunction in COVID-19: A potential predictor of long-COVID?|2021|Seitz A,Ong P,|

COVID-19 and liver dysfunction: What nutritionists need to know.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048466
World Journal of Gastroenterology; Wang MK, Yu XL et. al.

May 19th, 2022 - The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus-2 has brought serious challenges for the medical field. Patients with COVID-19 usually have respiratory symptoms. However, liver dysfunction is not an uncommon presentation. Additionally, the degree of liver dysfunction is associated with the ...

Clinical effectiveness of COVID-19 vaccination in solid organ tran...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420394
Transplant Infectious Disease : an Official Journal of Th... Aslam S, Adler E et. al.

Jul 30th, 2021 - We aimed to assess the incidence rate of coronavirus disease 2019 (COVID-19) in vaccinated versus unvaccinated solid organ transplant recipients (SOTR) at our center. We abstracted the following clinical data from our transplant registry from 1/1/2021 to 6/2/2021: demographics, details of COVID-19 vaccination, incidence of COVID-19, and re...

COVID-19 Vaccine Refusal and Organ Transplantation.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894498
American Journal of Kidney Diseases : the Official Journa... Ross LF

Mar 9th, 2022 - COVID-19 Vaccine Refusal and Organ Transplantation.|2022|Ross LF,|prevention & control,

An overview of COVID-19 in solid organ transplantation.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8855607
Clinical Microbiology and Infection : the Official Public... Bartelt L, van Duin D

Feb 22nd, 2022 - The COVID-19 pandemic has influenced the field of solid organ transplantation (SOT) in many ways. COVID-19 has led to programmatic impacts and changes in donor and recipient selection. Several studies have evaluated the course, optimal treatment, and prevention of COVID-19 in SOT recipients. To review the literature on COVID-19 in S...

Myocardial Injury in Severe COVID-19 Compared With Non-COVID-19...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864609
Circulation Metkus TS, Sokoll LJ et. al.

Nov 14th, 2020 - Knowledge gaps remain in the epidemiology and clinical implications of myocardial injury in coronavirus disease 2019 (COVID-19). We aimed to determine the prevalence and outcomes of myocardial injury in severe COVID-19 compared with acute respiratory distress syndrome (ARDS) unrelated to COVID-19. We included intubated patients with COVID-...

Endothelial Dysfunction in Covid-19 Infection.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802031
The American Journal of the Medical Sciences; Otifi HM, Adiga BK

Jan 31st, 2022 - COVID-19 is an evolving systemic inflammatory pandemic disease, predominantly affecting the respiratory system. Associated cardiovascular comorbid conditions result in severe to critical illness with mortality up to 14.8 % in octogenarians. The role of endothelial dysfunction in its pathogenesis has been proposed with laboratory and autopsy data, though initially it was tho...

Implications for Neuromodulation Therapy to Control Inflammation and Related Organ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250255
Journal of Cardiovascular Translational Research; Fudim M, Qadri YJ et. al.

May 28th, 2020 - COVID-19 is a syndrome that includes more than just isolated respiratory disease, as severe acute respiratory syndrome-coronavirus 2 (SARS-CoV2) also interacts with the cardiovascular, nervous, renal, and immune system at multiple levels, increasing morbidity in patients with underlying cardiometabolic conditions and inducing myocardial injury or dysfunction. Emerging evide...

Taste Dysfunction May Linger After COVID-19
https://www.medpagetoday.com/infectiousdisease/covid19/96549

Jan 6th, 2022 - Taste dysfunction may linger after acute COVID-19 infection and may not necessarily be a consequence of olfactory dysfunction, a cross-sectional study in Italy showed. In a group of people who reported losing their sense of taste for months after they had COVID, 42% were found to have true hypogeusia, reported Paolo Boscolo-Rizzo, MD, of the University of Trie...

Covid-19 Boosters - Where from Here?
https://doi.org/10.1056/NEJMe2203329
The New England Journal of Medicine; Offit PA

Apr 14th, 2022 - Covid-19 Boosters - Where from Here?|2022|Offit PA,|

COVID-19, Network Dysfunction and Neurodegeneration.
https://doi.org/10.1089/brain.2021.29030.ped
Brain Connectivity; Edison P

Dec 11th, 2021 - COVID-19, Network Dysfunction and Neurodegeneration.|2021|Edison P,|

COVID-19 related olfactory dysfunction.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711304
Current Opinion in Otolaryngology & Head and Neck Surgery; Karamali K, Elliott M et. al.

Dec 11th, 2021 - This article reviews the literature on COVID-19 related anosmia, focusing on the epidemiology, pathophysiology recovery rates, current available treatment options, and research regarding novel treatments. Loss of sense of smell is one of the most prevalent symptoms reported by patients after COVID-19 infection. Even though there is a high self-reported recovery rate,...

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