×
About 10 results

Comparison of Saliva and Nasopharyngeal Swab Nucleic...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811189
JAMA Internal Medicine; Butler-Laporte G, Lawandi A et. al.

Jan 15th, 2021 - Nasopharyngeal swab nucleic acid amplification testing (NAAT) is the noninvasive criterion standard for diagnosis of coronavirus disease 2019 (COVID-19). However, it requires trained personnel, limiting its availability. Saliva NAAT represents an attractive alternative, but its diagnostic performance is unclear. To assess the diagnostic accuracy of saliva...

Performance comparison of the Cobas® Liat® and Cepheid® GeneXpert® systems on SA...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8095157
Expert Review of Molecular Diagnostics; Tsang HF, Leung WMS et. al.

Apr 28th, 2021 - Background: Nucleic acid amplification tests (NAATs) based methods such as real-time reverse transcription polymerase-chain reaction (real-time RT-PCR) are the gold standard for diagnosis of current infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The cobas® Liat® and cepheid® GeneXpert® systems are two rapid real-time RT-PCR platforms offering rapid, s...

Evaluation of simple nucleic acid extraction methods for the detection of...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309780
Journal of Clinical Virology : the Official Publication O... Chu AW, Chan WM et. al.

Jul 6th, 2020 - The severe shortage of nucleic acid extraction kits during the current COVID-19 pandemic represents a key limiting factor in testing capacity. This study compared the results of SARS-CoV-2 RT-PCR using different simple nucleic acid extraction methods on nasopharyngeal and saliva specimens. Fifty nasopharyngeal swab and saliva specim...

Comparative evaluation of a dual-target real-time RT-PCR assay for COVID-19 diagnosis a...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182820
Expert Review of Molecular Diagnostics; Yip CCY, Leung KH et. al.

May 20th, 2021 - Objectives: Sensitive molecular diagnostic assays are essential for COVID-19 diagnosis. We evaluated the Hecin Scientific SARS-CoV-2 nucleic acid test kit, a dual-target real-time RT-PCR assay targeting the SARS-CoV-2 N and ORF1ab genes.Methods: The Hecin test kit's diagnostic performance in detecting SARS-CoV-2 RNA was compared to the LightMix Modular SARS and Wuhan CoV E-gene ki...

Use of throat swab or saliva specimens for detection of respiratory virus...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7107872
Clinical Infectious Diseases : an Official Publication Of... Robinson JL, Lee BE et. al.

Apr 30th, 2008 - Nasopharyngeal (NP) specimens are commonly used for the detection of respiratory viruses, but throat and saliva specimens are easier to obtain. The objective of this study was to compare the viral yield of direct fluorescent antigen detection of NP specimens and nucleic acid amplification tests (NAT) of direct fluorescent antigen-negative NP specimens with the viral ...

Comparison of saliva with oral and nasopharyngeal swabs for SARS-C...
https://doi.org/10.1002/jmv.27026
Journal of Medical Virology; Labbé AC, Benoit P et. al.

Apr 14th, 2021 - The accurate laboratory detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a crucial element in the fight against coronavirus disease 2019 (COVID-19). Reverse transcription-polymerase chain reaction testing on combined oral and nasopharyngeal swab (ONPS) suffers from several limitations, including the need for qualified personnel, the discomfort cause...

FDA Approves Emergency Use of Saliva Test to Detect COVID-19
https://emedicine.medscape.com/viewarticle/928760

Editor's note: Find the latest COVID-19 news and guidance in Medscape's  Coronavirus Resource Center. As the race to develop rapid testing for COVID-19 expands, the Food and Drug Administration has granted emergency approval for an approach that uses saliva as the primary test biomaterial. According to a document provided to the FDA, the Rutgers Clinical Genomics Laboratory TaqPath SARS-...

Saliva testing for SARS-CoV-2 in children.
https://doi.org/10.1016/j.cmi.2021.05.046
Clinical Microbiology and Infection : the Official Public... Clifford V, Curtis N

Jun 8th, 2021 - If found to have adequate sensitivity and specificity, saliva would be an ideal sample type for identifying SARS-CoV-2 and other respiratory viruses in children, as its collection is less invasive than other standard upper respiratory tract sample types such as nasopharyngeal swab (NPS), deep nasal/oropharyngeal swab or nasopharyngeal aspirate (NPA). At presen...

Fast Five Quiz: COVID-19 Clinical Keys
https://reference.medscape.com/viewarticle/939436_5

Oct 21st, 2020 - According to IDSA guidelines on the diagnosis of COVID-19, a SARS-CoV-2 nucleic acid amplification test is recommended in symptomatic individuals suspected of having COVID-19, even when the clinical suspicion for COVID-19 is low. The IDSA suggests collecting nasopharyngeal, mid-turbinate, or nasal swabs rather than oropharyngeal swabs or saliva alone fo...

Self-Collected Saline Gargle Samples as an Alternative to Health Care Worker-Collected ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092743
Journal of Clinical Microbiology; Goldfarb DM, Tilley P et. al.

Jan 30th, 2021 - We assessed the performance, stability, and user acceptability of swab-independent self-collected saliva and saline mouth rinse/gargle sample types for the molecular detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in adults and school-aged children. Outpatients who had recently been diagnosed with COVID-19 or were presenting with suspected COVID-19 were a...