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About 4,773 results

ALLMedicine: Cannabis Center

Interaction between warfarin and cannabis
https://onlinelibrary.wiley.com/doi/full/10.1111/bcpt.13152
Damkier,P.,et al

Oct 16th, 2018 - Delta‐9‐tetrahydrocannabinol (THC), the main psychoactive cannabinoid in cannabis, may inhibit the cytochrome P450 enzyme CYP2C9. Consequently, cannabis use might infer a risk of drug‐drug interaction with substrates for this enzyme, which includes drugs known to have a narrow therapeutic window. In this study, we describe a case report of a 27‐year‐old man treated with ...

Probable Interaction Between Warfarin and Inhaled and Oral Administration...
https://doi.org/10.1177/0897190019854958
Journal of Pharmacy Practice; Hsu A, Painter NA

Jul 20th, 2019 - To report a probable interaction between warfarin and edible cannabis that resulted in an elevated international normalized ratio (INR) without bleeding complications. Case Summary: A 35-year-old Middle Eastern male on warfarin long term with an INR goal of 2.5 (accepted range: 2.0-3.0). The patient has generally been stable on warfarin 10 mg daily from 2010 t...

Probable interaction between warfarin and marijuana smoking.
https://doi.org/10.1345/aph.1M064
The Annals of Pharmacotherapy; Yamreudeewong W, Wong HK et. al.

Jun 18th, 2009 - To report a probable interaction between warfarin and marijuana smoking, resulting in increased international normalized ratio (INR) values and bleeding complications. A 56-year-old white male had been receiving chronic warfarin therapy for 11 years after mechanical heart valve replacement. He was admitted to the hospital with a diagnosis of upper gastrointestinal bleeding....

Warfarin and Acetaminophen Interaction
https://www.medscape.com/viewarticle/448291

Abstract and Introduction A 74-year-old man who was receiving warfarin for atrial fibrillation experienced an abrupt increase in his international normalized ratio (INR) after taking acetaminophen. To investigate this effect, the patient's anticoagulation therapy was stabilized, and he was given acetaminophen 1 g 4 times/day for 3 days. His INR rose from 2.3 before receiving acetaminophe...

Warfarin and Acetaminophen Interaction
https://www.medscape.com/viewarticle/448291_3

Discussion The combined therapeutic use of warfarin and acetaminophen is very common, and a clinically significant drug interaction is a debated matter. Insufficient data have been acquired on this interaction in controlled experiments using INR determinations to monitor the level of anticoagulation. Many drugs routinely coadministered with warfarin interact by inhib...

Warfarin-cranberry juice interaction.
https://doi.org/10.1345/aph.1P451
The Annals of Pharmacotherapy; Hamann GL, Campbell JD et. al.

Mar 3rd, 2011 - To report a case of warfarin-cranberry juice interaction, which resulted in an international normalized ratio (INR) elevation on 2 separate occasions. A 46-year-old female was receiving a total weekly dose of 56 mg of warfarin. During the 4 months prior to the incident INR, her average INR was 2.0, with a range of 1.6-2.2, while taking the same weekly dose of warfarin...

Sprouting a warfarin interaction.
https://doi.org/10.1136/bmj.c2621
BMJ (Clinical Research Ed.); Kidd LR, Hanumantharaya DH

Jul 16th, 2010 - Sprouting a warfarin interaction.|2010|Kidd LR,Hanumantharaya DH,|adverse effects,adverse effects,adverse effects,chemically induced,chemically induced,drug therapy,etiology,adverse effects,

Direct Oral Anticoagulants Versus Warfarin in Patients With Atrial Fibrillation:...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800560
Circulation Carnicelli AP, Hong H et. al.

Jan 6th, 2022 - Direct oral anticoagulants (DOACs) are preferred over warfarin for stroke prevention in atrial fibrillation. Meta-analyses using individual patient data offer substantial advantages over study-level data. We used individual patient data from the COMBINE AF (A Collaboration Between Multiple Institutions to Better Investigate Non-Vitamin K Antagonist Oral Anticoagulant Use in Atrial Fibril...

A Test of Interaction Effects Between Cannabis Protective Behavioral Stra...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522187
Journal of Psychoactive Drugs; Richards DK, Schwebel FJ et. al.

Apr 20th, 2021 - The purpose of the present study was to examine tests of interaction effects between cannabis protective behavioral strategies use and a range of risk/protective factors for negative cannabis-related consequences. We recruited 2,226 college students (Mage = 20.28, SD = 3.37; 68.8% female; 75.4% White) from 10 universities throughout the U.S. who reported using cannabis...

Assessing evidence of interaction between smoking and warfarin: a systema...
https://doi.org/10.1378/chest.10-0777
Chest Nathisuwan S, Dilokthornsakul P et. al.

May 5th, 2011 - Chronic smoking, theoretically, can interfere with warfarin metabolism through enzyme-inducing effects of polycyclic aromatic hydrocarbons. However, clinical evidence of interactions between warfarin and smoking are inconclusive. This study aimed to systematically review all relevant clinical evidence of this interaction. We performed a systematic search using comput...

Bleeding interaction between fluconazole and warfarin.
https://doi.org/10.1016/S0140-6736(18)32217-7
Lancet (London, England); de Filette J, Michiels V

Oct 12th, 2018 - Bleeding interaction between fluconazole and warfarin.|2018|de Filette J,Michiels V,|adverse effects,adverse effects,adverse effects,chemically induced,chemically induced,adverse effects,

Probable warfarin and dapsone interaction.
https://doi.org/10.1177/1076029611418963
Clinical and Applied Thrombosis/hemostasis : Official Jou... Truong T, Haley J

Sep 6th, 2011 - We describe a case of a 41-year-old woman who was stable for over a year on 22.5 mg/week of warfarin. At a follow-up visit, her international normalized ratio (INR) was found to be supratherapeutic at 3.9. Her only significant change was acyclovir initiation for shingles, and clindamycin and dapsone for infection on her right foot. An interaction report was run using Micromedex wi...

CYP2C9-mediated warfarin and milk thistle interaction.
https://doi.org/10.1111/jcpt.13064
Journal of Clinical Pharmacy and Therapeutics; Lash DB, Ward S

Oct 22nd, 2019 - In vitro studies suggest a CYP2C9-mediated interaction between milk thistle and warfarin, but there has been no in vivo case report on this interaction. A White Hispanic man in his 30s was well controlled on warfarin therapy for mitral valve replacement. His INR increased from 2.64 to 4.12, and he denied changes to his medications and diet but noted starting a 'liver...

A case series of the rifampin-warfarin drug interaction: focus on practic...
https://doi.org/10.1007/s00228-020-03057-x 10.1378/chest.08-0670 10.15420/ecr.2017:11:2 10.1161/ATVBAHA.115.303397 10.3821/1913-701X-144.1.21 10.2174/1872312811206030002 10.1016/S0163-7258(96)00140-4 10.2165/00003088-197803020-00002 10.7326/0003-4819-82-2-224 10.1378/chest.67.4.490 10.1097/00007611-198810000-00024 10.1592/phco.21.15.1240.33897 10.1111/j.0889-7204.2007.05782.x 10.1177/0091270009353030 10.1097/00007611-199612000-00014 10.1186/2050-6511-14-27 10.1186/s40064-015-1653-8 10.1007/s40268-013-0023-7 10.5863/1551-6776-22.5.375
European Journal of Clinical Pharmacology; Yang CS, Boswell R et. al.

Jan 8th, 2021 - To provide practical guidance by providing weekly descriptions of warfarin requirements for the onset and offset of the rifampin-warfarin interaction. A retrospective chart review within an outpatient Anticoagulation Clinic (AC). Patients were eligible for the onset phase provided they had known ambulatory-based warfarin steady-state requirements prior to rifampin in...

Pickles and warfarin interaction: a case-based review.
https://doi.org/10.1007/s10067-020-05324-9 10.1001/archinte.165.10.1095 10.1016/S0735-1097(03)00416-9 10.1016/j.amjmed.2003.12.036 10.1378/chest.119.1_suppl.8S 10.1177/0897190014544823 10.1080/07315724.2000.10718944 10.4274/tjh.2015.0271 10.1182/bloodadvances.2018018036 10.1016/j.thromres.2011.01.014 10.1097/MD.0000000000002895 10.1016/j.jand.2015.12.023
Clinical Rheumatology; Rangecroft A, Prabhu SS et. al.

Aug 12th, 2020 - A 36-year-old woman with a history of lupus and antiphospholipid syndrome controlled by warfarin presented to the hospital with left periorbital ecchymosis. She was found to have an INR of 9 despite maintaining her normal warfarin dose of 12.5 mg/15 mg alternating qd. The only identifiable precipitating factor was that the patient recently stopped eating dill pickles. Limiting dietary vitamin K...

Repetitive negative thinking, metacognitive beliefs, and their interaction as po...
https://doi.org/10.1002/cpp.2664
Clinical Psychology & Psychotherapy; Hamonniere T, Milan L et. al.

Aug 26th, 2021 - The metacognitive formulation of addictive behaviours considers repetitive negative thinking (RNT) and metacognitive beliefs as two important processes involved in the development and maintenance of addictive behaviours. To date, very limited research has investigated the implication of these processes in problematic cannabis use. The present study was aimed at exploring the association between...

Flucloxacillin-warfarin interaction: an under-appreciated phenomenon.
https://doi.org/10.1111/imj.13944
Internal Medicine Journal; Chaudhuri A, Wade SL

Jul 10th, 2018 - Current drug databases do not acknowledge an interaction between warfarin and flucloxacillin although case reports have indicated that flucloxacillin may increase warfarin requirement to maintain therapeutic international normalised ratio (INR). To assess whether flucloxacillin therapy leads to a significant increase in warfarin dose, we conducted a retrospective, ob...

Beware warfarin interaction with antibiotics, acetaminophen, steroids
https://www.mdedge.com/cardiology/article/58635/arrhythmias-ep/beware-warfarin-interaction-antibiotics-acetaminophen
Sherry Boschert

May 2nd, 2013 - SAN FRANCISCO – The main reason older U. S.

Association of Intracerebral Hemorrhage Among Patients Taking Non-Vitamin K Antagonist ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839299
JAMA Inohara T, Xian Y et. al.

Jan 27th, 2018 - Although non-vitamin K antagonist oral anticoagulants (NOACs) are increasingly used to prevent thromboembolic disease, there are limited data on NOAC-related intracerebral hemorrhage (ICH). To assess the association between preceding oral anticoagulant use (warfarin, NOACs, and no oral anticoagulants [OACs]) and in-hospital mortality among patients with ICH. Retrospective cohort study of...

In vitro evaluation of the interaction of the cannabis constituents canna...
https://doi.org/10.1016/j.ejphar.2022.174836
European Journal of Pharmacology; Etchart MG, Anderson LL et. al.

Mar 21st, 2022 - Cannabichromene (CBC) and cannabichromenic acid (CBCA) are cannabis constituents currently under evaluation for their therapeutic potential, but their pharmacological properties have not been thoroughly investigated. The most studied ATP-binding cassette (ABC) transporters, ABC subfamily G member 2 (ABCG2) and ABC subfamily B member 1 (ABCB1) limit absorption of substrate drugs in the gut and b...