About 1,740,493 results

Cannabinoids for Medical Use: A Systematic Review and Meta-analysis.
JAMA Whiting PF, Wolff RF et. al.

Jun 24th, 2015 - Cannabis and cannabinoid drugs are widely used to treat disease or alleviate symptoms, but their efficacy for specific indications is not clear. To conduct a systematic review of the benefits and adverse events (AEs) of cannabinoids. Twenty-eight databases from inception to April 2015. Randomized clinical trials of cannabinoids for the following indications: nausea and vomiting due to chemother...

Medical Cannabinoids in Children and Adolescents: A Systematic Review.
Pediatrics Wong SS, Wilens TE

Oct 25th, 2017 - Legalization of medical marijuana in many states has led to a widening gap between the accessibility and the evidence for cannabinoids as a medical treatment. To systematically review published reports to identify the evidence base of cannabinoids as a medical treatment in children and adolescents. Based on Preferred Reporting Items for Systematic Reviews and ...

Medical Use of Cannabinoids
Drugs Fraguas-Sánchez,A.,et al

Oct 29th, 2018 - Cannabinoid receptors, endocannabinoids and the enzymes responsible for their biosynthesis and degradation constitute the endocannabinoid system. In recent decades, the endocannabinoid system has attracted considerable interest as a potential therapeutic target in numerous pathological conditions. Its involvement in several physiological processes is well known, such as in energy balance...

Medical Use of Cannabinoids.
Drugs Fraguas-Sánchez AI, Torres-Suárez AI

Oct 31st, 2018 - Cannabinoid receptors, endocannabinoids and the enzymes responsible for their biosynthesis and degradation constitute the endocannabinoid system. In recent decades, the endocannabinoid system has attracted considerable interest as a potential therapeutic target in numerous pathological conditions. Its involvement in several physiological processes is well known, such as in energy balance...

Medical cannabis and cannabinoids in rheumatology: where are we now?
Expert Review of Clinical Immunology; Sarzi-Puttini P, Batticciotto A et. al.

Sep 13th, 2019 - Introduction: Clinicians involved in pain management can finally include cannabis or cannabis-related products in their therapeutic armamentarium as a growing number of countries have approved them for pain relief. Despite the several benefits attributed to analgesic, anti-inflammatory and immunomodulatory properties of cannabinoids, there are still significant areas of uncertainty conce...

Effects of Cannabinoids on Female Sexual Function.
Sexual Medicine Reviews; Lynn B, Gee A et. al.

Sep 16th, 2019 - With the legalization of both medical and recreational marijuana in some countries and a few US states, its use has become more widely prevalent. Both exogenous cannabinoids such as tetrahydrocannabinol (THC) and endogenous cannabinoids (endocannabinoids) have been shown to affect female gonadotropin pathways and female sexuality. Yet, our understanding of the mechan...

Cannabinoids in Pain Treatment: An Overview.
Pain Management Nursing : Official Journal of the America... Mallick-Searle T, St Marie B

May 1st, 2019 - The current landscape contains conflicting reports regarding the use of medical marijuana, creating fields of misinformation and lack of understanding by health care providers about cannabinoids. In this article we provide a dispassionate look at medical marijuana, while providing a clinical overview focusing on pain management. We examine the mechanisms of the endocannabin...

A review of oral cannabinoids and medical marijuana for the treatment of ...
Cancer Chemotherapy and Pharmacology; Badowski ME

Aug 7th, 2017 - Oral cannabinoids (i.e., dronabinol, nabilone) containing the active component of marijuana, delta(Δ)9-tetrahydrocannabinol (THC), are available for the treatment of chemotherapy-induced nausea and vomiting (CINV) in patients with cancer who have failed to adequately respond to conventional antiemetic therapy. The aim of this article is to provide an overview of the efficacy, pharmacokin...

The Trouble with CBD Oil
Medical Cannabis and Cannabinoids; Hazekamp,A.,et al

Sep 1st, 2018 - In just a few years, cannabidiol (CBD) has become immensely popular around the world. After initially being discovered as an effective self-medication for Dravet syndrome in children, CBD is now sold and used to treat a wide range of medical conditions and lifestyle diseases. The cannabinoid CBD, a non-psychoactive isomer of the more infamous tetrahydrocannabinol (THC), is available in a...

Medical cannabinoids.
CMAJ : Canadian Medical Association Journal = Journal De ... McLeod SA, Lemay JF

Aug 2nd, 2017 - Medical cannabinoids.|2017|McLeod SA,Lemay JF,|adverse effects,therapeutic use,adverse effects,therapeutic use,drug therapy,adverse effects,therapeutic use,

Cannabinoids for Pain Control During Medical Abortion: A Randomized Contr...
Obstetrics and Gynecology; Colwill AC, Alton K et. al.

May 28th, 2020 - To evaluate whether prophylactic dronabinol, a synthetic tetrahydrocannabinol, reduces pain during medical abortion. We conducted a randomized, double-blind, placebo-controlled trial of women undergoing medical abortion with mifepristone and misoprostol up through 70 days of gestation. All participants received 800 mg of ibuprofen and were randomized to either 5 mg of oral dronabi...

Focus on cannabinoids and synthetic cannabinoids.
Clinical Pharmacology and Therapeutics; Le Boisselier R, Alexandre J et. al.

Nov 20th, 2016 - The recent emergence of a multitude of synthetic cannabinoids (SCs) has generated a wealth of new information, suggesting the usefulness of state-of-the-art on lato sensu cannabinoids. By modulating a plurality of neurotransmission pathways, the endocannabinoid system is involved in many physiological processes that are increasingly explored. SCs desired and adverse effects are co...

Increase in Adverse Reactions Associated with Use of Synthetic Cannabinoids - An...
MMWR. Morbidity and Mortality Weekly Report; Springer YP, Gerona R et. al.

Oct 14th, 2016 - In July 2015, personnel in the Alaska Division of Public Health's Section of Epidemiology became aware of an increase in the number of patients being treated in Anchorage hospital emergency departments for adverse reactions associated with use of synthetic cannabinoids (SCs). SCs are a chemically diverse class of designer drugs that bind to the same cannabinoid receptors as tetrahydrocan...

Medical cannabis or cannabinoids for chronic pain: a clinical practice gu...
BMJ (Clinical Research Ed.); Busse JW, Vankrunkelsven P et. al.

Sep 10th, 2021 - What is the role of medical cannabis or cannabinoids for people living with chronic pain due to cancer or non-cancer causes? Chronic pain is common and distressing and associated with considerable socioeconomic burden globally. Medical cannabis is increasingly used to manage chronic pain, particularly in jurisdictions that have enacted policies to reduce use of opioids; how...

Should Medical Marijuana and Cannabinoids Be Used to Treat Epilepsy?

Jun 28th, 2016 - VANCOUVER—“Neurologists are often asked to ‘certify’ patients, but should you recommend or support medical marijuana use for patients with epilepsy?” Daniel Friedman, MD, MSc, Assistant Professor of Neurology at New York University Langone School of Medicine in New York, addressed this question in his presentation at the 68th Annual Meeting of the American Academy of Neurology. Daniel Fr.

Medical cannabinoids for treatment of neuropsychiatric symptoms in dement...
Trends in Psychiatry and Psychotherapy; Stella F, Valiengo LCL et. al.

Aug 11th, 2021 - Neuropsychiatric symptoms are an integral component of the natural history of dementia, occurring from prodromal to advanced stages of the disease process and causing increased burden and morbidity. Clinical presentations are pleomorphic and clinical management often requires combinations of pharmacological and non-pharmacological interventions. However, limited efficacy and a non-negligible in...

Cannabinoids for neuropathic pain.
Current Pain and Headache Reports; Fine PG, Rosenfeld MJ

Aug 28th, 2014 - Treatment options for neuropathic pain have limited efficacy and use is fraught with dose-limiting adverse effects. The endocannabinoid system has been elucidated over the last several years, demonstrating a significant interface with pain homeostasis. Exogenous cannabinoids have been demonstrated to be effective in a range of experimental neuropathic pain models, and there is mounting e...

Only moderate-quality evidence supports medical cannabinoids
Mary Ann Moon, MDedge News

Jun 23rd, 2015 - At best, only moderate-quality evidence supports the use of medical cannabinoids, and for only two conditions. And low-quality evidence only “suggests” that these agents may improve other medical conditions, but that limited effectiveness applies only to the four conditions that have been studied, according to a report published online June 23 in JAMA.

Safety and Toxicology of Cannabinoids.
Neurotherapeutics : the Journal of the American Society F... Sachs J, McGlade E et. al.

Aug 14th, 2015 - There is extensive research on the safety, toxicology, potency, and therapeutic potential of cannabis. However, uncertainty remains facilitating continued debate on medical and recreational cannabis policies at the state and federal levels. This review will include a brief description of cannabinoids and the endocannabinoid system; a summary of the acute and long-term effects of c...

The role of cannabinoids in dermatology.
Journal of the American Academy of Dermatology; Mounessa JS, Siegel JA et. al.

Apr 19th, 2017 - The role of cannabinoids in dermatology.|2017|Mounessa JS,Siegel JA,Dunnick CA,Dellavalle RP,|pharmacology,therapeutic use,drug therapy,