×
About 418 results

More alcohol, less brain: Penn-led study finds an association that begins with an average of just one drink a day
https://www.eurekalert.org/news-releases/945035

Mar 4th, 2022 - The science on heavy drinking and the brain is clear: The two don’t have a healthy relationship. People who drink heavily have alterations in brain structure and size that are associated with cognitive impairments. But according to a new study, alcohol consumption even at levels most would consider modest—a few beers or glasses of wine a week—may also carry risks to ...

Findings of a VCU study reveal the true burden of the hidden pandemic of fatty liver disease
https://www.eurekalert.org/news-releases/931679

Oct 20th, 2021 - RICHMOND, Va. (October 20, 2021) — A longitudinal national study led by Virginia Commonwealth University researcher Arun Sanyal, M.D., shows that people with advanced liver scarring caused by obesity, diabetes and related disorders are dying of liver disease. Published in the New England Journal of Medicine, the research brings new urgency to tests for liver disease, particularly in popu...

Study reveals brain cells that sustain or suppress fearful memories
https://www.nih.gov/news-events/nih-research-matters/study-reveals-brain-cells-sustain-or-suppress-fearful-memories

Jun 8th, 2021 - Remembering a threat is key for survival. Fearful memories help people and animals respond to potential dangers. But having these memories fade when they’re no longer useful is important to avoid undue stress and anxiety. When traumatic memories persist, they can lead to conditions like PTSD, anxiety disorders, and related problems like alcohol use disorder. In past studies, researchers identif...

Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331050
JAMA Psychiatry; Zhou H, Polimanti R et. al.

Oct 27th, 2017 - Alcohol dependence (AD) and major depression (MD) are leading causes of disability that often co-occur. Genetic epidemiologic data have shown that AD and MD share a common possible genetic cause. The molecular nature of this shared genetic basis is poorly understood. To detect genetic risk variants for comorbid AD and MD and to determine whether polygenic risk alleles are shared with neu...

Is Alcohol and Other Substance Use Reduced When College Students Attend Alcohol-Free Pr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129232
Prevention Science : the Official Journal of the Society ... Layland EK, Calhoun BH et. al.

Mar 9th, 2018 - College drinking and its negative consequences remain a major public health concern. Yet, many prevention efforts targeting college drinkers are expensive, are difficult to implement, use indicated approaches targeting only high-risk drinkers, and/or are only marginally effective. An alternative strategy taken explicitly or implicitly by many colleges is campus-led alcohol-free pr...

New Data on Alcohol and the Brain
https://www.medscape.com/viewarticle/882497

Jul 6th, 2017 - Moderate Alcohol Consumption as Risk Factor for Adverse Brain Outcomes and Cognitive Decline: Longitudinal Cohort Study Topiwala A, Allan CL, Valkanova V, et al BMJ. 2017;357:j2353 Summary The reported health effects of drinking alcohol are varied, with clear deleterious effects of heavy drinking on the brain, liver, and other organ systems, and some suggestion of benefit at low l...

Heavy Drinking Tied to Early-Onset Dementia in French Study
https://www.medpagetoday.com/neurology/dementia/71281

Feb 20th, 2018 - Heavy drinking may be a major risk factor for all types of dementia, especially early-onset dementia, retrospective research from France suggested. Of 57,000 people diagnosed before age 65 with early-onset dementia, 39% had alcohol-related dementia by definition, and 18% had an additional diagnosis of alcohol use disorders, reported Michaël Schwarzinger, PhD, of the Translational ...

Stroke Prevention
https://www.ncbi.nlm.nih.gov/books/NBK470234/
StatPearls; Ayan Sabih, Prasanna Tadi et. al.

Sep 29th, 2021 - There is a significant overlap between the risk factors accounting for cardiovascular events and cerebrovascular events. The INTERHEART study looked at nearly 30,000 patients divided into control and interventional groups to identify these risk factors. Stroke prevention follows a similar principle of controlling these risk factors. Risk factors important in stroke prevention can be divi...

Cluster Headache
https://www.ncbi.nlm.nih.gov/books/NBK544241/
StatPearls; Sharon A. Kandel, Pujyitha Mandiga

Jun 29th, 2021 - Cluster headaches are the most common of the primary headache type known as trigeminal autonomic cephalgia. They are fairly rare, plaguing 0.1% of the population, making a study of the disease process difficult at best. They are considered one of if not the most severe type of headache, and so, despite their rarity, recognition and treatment are vital. This activity reviews the evaluation, trea...

Lacunar Stroke
https://www.ncbi.nlm.nih.gov/books/NBK563216/
StatPearls; Meghana Gore, Kamna Bansal et. al.

Sep 28th, 2021 - Lacunar stroke is a common stroke with significant morbidity and mortality. Advancement in knowledge about modifying risk factors and early diagnosis has led to a favorable outcome. This article reviews the pathophysiology, diagnosis, and management options and highlights the role of the interprofessional team in treating patients suffering from a lacunar stroke. Objectives: Stro...

Cedars-Sinai May research highlights
https://www.eurekalert.org/news-releases/954112

May 26th, 2022 - A new study led by Ophir Klein, MD, PhD, executive director of Cedars-Sinai Guerin Children's, identified a gene that plays an important role in a biological pathway involved in embryo development. The findings could explain why some babies are born with physical abnormalities and why some adults develop diseases such as cancer. The study is published in Nature Communicatio...

UTSA collaborative study with DoD and VA aims to heighten awareness, improve care for veterans with traumatic brain injury
https://www.eurekalert.org/news-releases/943818

Feb 17th, 2022 - (San Antonio, February 17, 2022) – Emerging evidence from a study led by Jeffrey Howard, associate professor of public health in the UTSA College for Health, Community and Policy (HCaP), suggests that harmful exposures during military service such as traumatic brain injury (TBI) may contribute to long-term mental health, chronic disease and mortality risks. This is the firs...

Oncology Care Evolves as Lasting COVID-19 Effects Come Into Focus
https://www.onclive.com/view/oncology-care-evolves-as-lasting-covid-19-effects-come-into-focus-

Mar 9th, 2022 - The pandemic appears to have caused or contributed to a number of lasting changes in the way oncologists provide clinical care to their patients. But clinicians note that as the nature of the health crisis continues to evolve any shifts in treatment patterns or methods instituted to lower the risk of COVID-19 infection must be supported with data showing they provide the best possible outcomes....

LateNight Penn State alcohol-free programming: students drink less on days they partici...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063607
Prevention Science : the Official Journal of the Society ... Patrick ME, Maggs JL et. al.

Dec 19th, 2009 - Despite the public health importance of alcohol-free social programs for college students, the majority of existing campus strategies have not been empirically evaluated. This study utilized repeated daily reports to examine the association between attendance at campus-led alcohol-free programming and alcohol use on specific days while controlling for i...

Evidence of CNIH3 involvement in opioid dependence.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740268
Molecular Psychiatry; Nelson EC, Agrawal A et. al.

Aug 5th, 2015 - Opioid dependence, a severe addictive disorder and major societal problem, has been demonstrated to be moderately heritable. We conducted a genome-wide association study in Comorbidity and Trauma Study data comparing opioid-dependent daily injectors (N=1167) with opioid misusers who never progressed to daily injection (N=161). The strongest associations, observed for...

Machine Learning May Improve Schizophrenia Diagnosis
https://www.staging.medscape.com/viewarticle/883788

Aug 4th, 2017 - A machine learning approach that uses artificial intelligence (AI) to examine millions of brain cortical links can identify schizophrenia cases with a high degree of accuracy and predict symptom severity, new research shows. In a brain imaging analysis, investigators led by Irina Rish, PhD, IBM T. J. Watson Research Center, Yorktown Heights, New York, found that, through us...

Neuromodulation Surgery For Psychiatric Disorders
https://www.ncbi.nlm.nih.gov/books/NBK482366/
StatPearls; Orlando De Jesus, Delvise T. Fogwe et. al.

Sep 3rd, 2021 - Clinicians are beginning to reconsider neuromodulation surgery as a last resort for the treatment of refractory psychiatric disorders. Neurosurgical interventions aimed at treating psychiatric disorders are grouped into two categories: destructive (ablative psychosurgery) or selective stimulation (neuromodulation psychosurgery). Neuromodulation surgery involves implanting a device in the bra...

Clonidine hydrochloride - clonidine hydrochloride tablet-Bryant Ranch Prepack
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=be6c29cd-1692-4dd3-868e-7efcb3a85056

Dec 27th, 2021 - SPL PRODUCT DATA ELEMENTS SECTION Structure Description Section Clonidine hydrochloride is a centrally acting alpha-agonist hypotensive agent available as tablets for oral administration in three dosage strengths: 0.1 mg, 0.2 mg and 0.3 mg. The 0.1 mg tablet is equivalent to 0.087 mg of the free base. The inactive ingredients are lactose monohydrate, microcrystalline cellulose, pregelatinized...

Agitation
https://www.ncbi.nlm.nih.gov/books/NBK493153/
StatPearls; Waquar Siddiqui, Vikas Gupta et. al.

Aug 26th, 2021 - Agitation is a nonspecific constellation of relatively unrelated behaviors that can be seen in various clinical situations, usually presenting with a fluctuating course. This activity reviews the evaluation and management of agitation and highlights the role of the interprofessional team in the recognition and management of agitation. Objectives: Agitation is a feeling of irritability or sever...

Substance Use In Pregnancy
https://www.ncbi.nlm.nih.gov/books/NBK542330/
StatPearls; Mary K. Prince, Derek Ayers

Jul 10th, 2021 - Substance use disorder (SUD) in pregnancy is a growing concern in the United States. Patients with substance use disorders in the peripartum period face unique barriers to care, and have unique co-morbidities. This activity reviews the evaluation and management of the most common substance use disorders in pregnancy. Additionally, this activity reviews co-morbidities commonly associated with su...