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About 2,910 results

Rates of serious clinical outcomes in survivors of hospitalisation with COVID-19: a descriptive cohort study within the OpenSAFELY platform
https://www.medrxiv.org/content/10.1101/2021.01.22.21250304v2
Medrxiv The OpenSAFELY Collaborative

Jan 25th, 2021 - Background Patients with COVID-19 are thought to be at higher risk of cardiometabolic and pulmonary complications, but quantification of that risk is limited. We aimed to describe the overall burden of these complications in survivors of severe COVID-19.

Long-term clinical outcomes in survivors of severe acute respirato...
https://doi.org/10.2340/16501977-2694
Journal of Rehabilitation Medicine; Ahmed H, Patel K et. al.

May 26th, 2020 - To determine long-term clinical outcomes in survivors of severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) coronavirus infections after hospitalization or intensive care unit admission. Ovid MEDLINE, EMBASE, CINAHL Plus, and PsycINFO were searched. Original studies reporting clinical outcomes of adult SARS and MERS survivors 3 months after admission or 2 month...

Recent trends in survival from out-of-hospital cardiac arrest in the United States.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276415
Circulation Chan PS, McNally B et. al.

Nov 17th, 2014 - Despite intensive efforts over many years, the United States has made limited progress in improving rates of survival from out-of-hospital cardiac arrest. Recently, national organizations, such as the American Heart Association, have focused on promoting bystander cardiopulmonary resuscitation, use of automated external defibrillators, and other performance improvement efforts. Using the...

Association Between Transcatheter Aortic Valve Replacement and Subsequent Infective End...
https://doi.org/10.1001/jama.2016.12347
JAMA Regueiro A, Linke A et. al.

Sep 14th, 2016 - Limited data exist on clinical characteristics and outcomes of patients who had infective endocarditis after undergoing transcatheter aortic valve replacement (TAVR). To determine the associated factors, clinical characteristics, and outcomes of patients who had infective endocarditis after TAVR. The Infectious Endocarditis after TAVR International Registry included ...

Early surgery and neurodevelopmental outcomes of children born extremely preterm.
https://doi.org/10.1136/archdischild-2017-313161
Archives of Disease in Childhood. Fetal and Neonatal Edit... Hunt RW, Hickey LM et. al.

Jul 25th, 2017 - To (1) compare the neurodevelopmental outcomes at 8 years of age of children born extremely preterm (EP) who underwent surgical procedures during the course of their initial hospital admission with those who did not and (2) compare the outcomes across eras, from 1991 to 2005. Prospective observational cohort studies conducted over three different eras (1991-1992, 1997 and 2005). Surviving EP ch...

Effect of Moderate vs Mild Therapeutic Hypothermia on Mortality and Neurologic Outcomes...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527358
JAMA Le May M, Osborne C et. al.

Oct 20th, 2021 - Comatose survivors of out-of-hospital cardiac arrest experience high rates of death and severe neurologic injury. Current guidelines recommend targeted temperature management at 32 °C to 36 °C for 24 hours. However, small studies suggest a potential benefit of targeting lower body temperatures. To determine whether moderate hypothermia (31 °C), compared with mild hypothermia (34 °...

High-degree atrioventricular block complicating ST segment elevation myocardial infarct...
https://doi.org/10.1136/heartjnl-2015-308260
Heart (British Cardiac Society); Auffret V, Loirat A et. al.

Dec 15th, 2015 - High-degree atrioventricular block (HAVB) is a common complication of ST segment elevation myocardial infarction (STEMI). HAVB in STEMI is historically considered as a marker of worse outcome but overall data about HAVB in the contemporary era of mechanical reperfusion and potent antiplatelet therapies are scarce. Analysing incidence, clinical correlates and impact on inhospital outco...

Effects of oral anticoagulation for atrial fibrillation after spontaneous intracranial ...
https://doi.org/10.1016/S1474-4422(21)00264-7
The Lancet. Neurology;

Sep 7th, 2021 - Oral anticoagulation reduces the rate of systemic embolism for patients with atrial fibrillation by two-thirds, but its benefits for patients with previous intracranial haemorrhage are uncertain. In the Start or STop Anticoagulants Randomised Trial (SoSTART), we aimed to establish whether starting is non-inferior to avoiding oral anticoagulation for survivors of intracranial haemorrhage who hav...

Female cancer survivors are low responders and have reduced success compared with other...
https://doi.org/10.1016/j.fertnstert.2011.11.028
Fertility and Sterility; Barton SE, Missmer SA et. al.

Dec 20th, 2011 - To investigate the effect of prior chemotherapy and radiation on assisted reproductive technology (ART) outcomes. Retrospective cohort study. University-based infertility clinic. Female cancer survivors who had received chemotherapy or radiation and all other women undergoing first-fresh IVF/intracytoplasmic sperm injection (ICSI) cycles. Survivors' ART outcomes were...

Pyogenic vertebral osteomyelitis of the elderly: Characteristics and outcomes.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716588
PloS One; Courjon J, Lemaignen A et. al.

Dec 6th, 2017 - The incidence of pyogenic vertebral osteomyelitis (PVO) has increased over the past two decades. One possible cause of this increase is the aging of the population, which results in more comorbidities in high income countries. To better characterize the clinical presentation and outcome of PVO in the elderly. We conducted a post-hoc analysis of a previously published trial that studied t...

Second cranio-facial malignancies in hereditary retinoblastoma survivors previously tre...
https://doi.org/10.1016/j.ejca.2013.01.010
European Journal of Cancer (Oxford, England : 1990); Rodjan F, Graaf Pd et. al.

Feb 19th, 2013 - Hereditary retinoblastoma survivors have an increased risk for cranio-facial second primary tumours (SPT), especially after treatment with external beam radiotherapy (EBRT). This multicentre study evaluates the clinical and imaging characteristics and outcomes of cranio-facial SPTs in irradiated retinoblastoma survivors. Clinical and radiological data of 42 he...

Natural course of noncurative endoscopic resection of differentiated early gastric cancer.
https://doi.org/10.1055/s-0032-1325676
Endoscopy Ahn JY, Jung HY et. al.

Nov 29th, 2012 - Following noncurative endoscopic resection of early gastric cancer (EGC), the patient should be observed when the underlying disease is severe, the patient is elderly, or the patient refuses further treatment. The aim of this study was to analyze the clinical outcomes of patients with differentiated EGC who underwent noncurative endoscopic resection without additional treatment. Included patien...

Laparoscopy-assisted vs. open total gastrectomy for advanced gastric cancer: long-term ...
https://doi.org/10.1007/s11605-013-2218-1
Journal of Gastrointestinal Surgery : Official Journal Of... Bo T, Peiwu Y et. al.

May 18th, 2013 - An increasing number of studies comparing laparoscopy-assisted distal gastrectomy and conventional open distal gastrectomy have been reported; the technical feasibility and clinical efficacy have been confirmed. However, few data are available to compare laparoscopy-assisted total gastrectomy (LATG) and open techniques for the treatment of advanced gastric cancer (AGC). The aim of this study is...

Clinical outcomes of adult survivors of pulmonary atresia with intact ventricular septum.
https://doi.org/10.1016/j.ijcard.2011.04.026
International Journal of Cardiology; John AS, Warnes CA

May 21st, 2011 - There are no studies on the long term clinical outcomes and complications in the adult patient with pulmonary atresia with intact ventricular septum (PA/IVS). This study reviews our experience with a limited group of adult survivors of PA/IVS seen in our adult congenital clinics. Twenty adult patients with PA/IVS (1998 to 2009) were identified from Mayo Clinic adult congeni...

Investigating risk factors for psychological morbidity three months after intensive car...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682294
Critical Care (London, England); Wade DM, Howell DC et. al.

Oct 17th, 2012 - There is growing evidence of poor mental health and quality of life among survivors of intensive care. However, it is not yet clear to what extent the trauma of life-threatening illness, associated drugs and treatments, or patients' psychological reactions during intensive care contribute to poor psychosocial outcomes. Our aim was to investigate the relative contributions of a bro...

Prazosin for Veterans with Posttraumatic Stress Disorder and Comorbid Alcohol Dependenc...
https://doi.org/10.1111/acer.12926
Alcoholism, Clinical and Experimental Research; Petrakis IL, Desai N et. al.

Dec 20th, 2015 - Posttraumatic stress disorder (PTSD) is an important and timely clinical issue particularly for combat veterans. Few pharmacologic options are available to treat PTSD, particularly among military personnel, and they are not based on rational neurobiology. The evidence for noradrenergic dysregulation in PTSD is strong, and the alpha-adrenergic agonist prazosin is one of the most promising...

A risk scoring system to predict in-hospital mortality in patients with cirrhosis prese...
https://doi.org/10.1097/MCG.0000000000000014
Journal of Clinical Gastroenterology; Lyles T, Elliott A et. al.

Nov 1st, 2013 - We aimed to develop a simple and practical risk scoring system to predict in-hospital mortality in cirrhotics presenting with upper gastrointestinal (GI) bleeding. Extensive clinical data were captured in patients with documented cirrhosis who underwent endoscopic evaluation for upper GI bleeding between January 1, 2003 and June 30, 2011 at Parkland Memorial Hospital. Predictors of mortality we...

Refractory Intracranial Hypertension: The Role of Decompressive Craniectomy.
https://doi.org/10.1213/ANE.0000000000002399
Anesthesia and Analgesia; Smith M

Aug 15th, 2017 - Raised intracranial pressure (ICP) is associated with worse outcomes after acute brain injury, and clinical guidelines advocate early treatment of intracranial hypertension. ICP-lowering therapies are usually administered in a stepwise manner, starting with safer first-line interventions, while reserving higher-risk options for patients with intractable intracranial hypertension. ...

Neurodevelopmental outcomes at 4 to 8 years of children born at 22 to 25 weeks' gestati...
https://doi.org/10.1001/jamapediatrics.2013.2395
JAMA Pediatrics; Moore GP, Lemyre B et. al.

Aug 28th, 2013 - Many centers delivering infants at 22 to 25 weeks' gestation have limited data regarding their outcomes. A meta-analysis of the 4- to 8-year neurodevelopmental outcomes and exploration of the limitations of meta-analysis would aid physicians and parents to plan care for these infants. To determine the rate of moderate to severe and severe neurodevelopmental impairment by gestation...

Global epidemiology of pediatric severe sepsis: the sepsis prevalence, outcomes, and th...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451622
American Journal of Respiratory and Critical Care Medicine; Weiss SL, Fitzgerald JC et. al.

Mar 4th, 2015 - Limited data exist about the international burden of severe sepsis in critically ill children. To characterize the global prevalence, therapies, and outcomes of severe sepsis in pediatric intensive care units to better inform interventional trials. A point prevalence study was conducted on 5 days throughout 2013-2014 at 128 sites in 26 countries. Patients younger than 18 years of age wit...