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ALLMedicine: Dementia Center

Study suggests lithium may decrease risk of developing dementia
https://www.eurekalert.org/news-releases/946590

Mar 17th, 2022 - Researchers have identified a link suggesting that lithium could decrease the risk of developing dementia, which affects nearly one million people in the UK. The researchers, from the University of Cambridge, conducted a retrospective analysis of the health records of nearly 30,000 patients from Cambridgeshire and Peterborough NHS Foundation Trust. The patient...

Lithium Linked to Small Reduction in Dementia Onset
https://www.medscape.com/viewarticle/970478

Mar 17th, 2022 - Lithium could be linked to a decrease in the risk of developing dementia for some people, according to a small study. Researchers at the University of Cambridge described their preliminary findings as "promising" and said that they justified conducting larger, randomised trials to test the results. Lithium has been proposed as a possible preventa...

Old Drug May Hold New Promise in Alzheimer's Disease
https://www.staging.medscape.com/viewarticle/741621

Apr 27th, 2011 - April 28, 2011 — Low-dose lithium appears to slow the progression of memory loss and cognitive decline in individuals with amnestic mild cognitive impairment (aMCI), a significant risk factor for Alzheimer's disease (AD), a new study suggests. A randomized, placebo-controlled trial showed treatment with lithium, an old drug historically used to treat bipolar d...

Automated analysis of propositional idea density in older adults.
https://doi.org/10.1016/j.cortex.2021.09.018
Cortex; a Journal Devoted to the Study of the Nervous Sys... Hill E, Alty J et. al.

Nov 15th, 2021 - Previous research suggests oral and written language can act as barometers of an individual's cognitive function, potentially providing a screening tool for the earliest stages of Alzheimer's disease (AD) and other forms of dementia. Idea density is a measure of the rate at which ideas, or elementary predications, are expressed and may provide an ideal measure for early detection ...

Lithium in Drinking Water May Lower Dementia Risk
https://emedicine.medscape.com/viewarticle/884607

Higher long-term lithium exposure from drinking water may be associated with a lower incidence of dementia, a large population-based study suggests. "This is the first study ever investigating the association between lithium in drinking water and onset of dementia," Lars Vedel Kessing, MD, DMSc, from the University of Copenhagen, Denmark, told Me...

Simple Language Test May Predict Alzheimer's Years Before Symptoms
https://www.staging.medscape.com/viewarticle/939618

Oct 22nd, 2020 - A simple language test developed using artificial intelligence (AI) is able to predict, with a high level of accuracy, which cognitively normal individuals will go on to develop Alzheimer's disease (AD), new research suggests. The findings show that the test has a 70% accuracy rate in predicting AD onset years before cognitive decline begins and is more accurate than traditional predictive meth...

Old Drug May Hold New Promise in Alzheimer's Disease
https://www.medscape.com/viewarticle/741621

Apr 27th, 2011 - April 28, 2011 — Low-dose lithium appears to slow the progression of memory loss and cognitive decline in individuals with amnestic mild cognitive impairment (aMCI), a significant risk factor for Alzheimer's disease (AD), a new study suggests. A randomized, placebo-controlled trial showed treatment with lithium, an old drug historically used to treat bipolar d...

Old Drug May Hold New Promise in Alzheimer's Disease
https://emedicine.medscape.com/viewarticle/741621

April 28, 2011 — Low-dose lithium appears to slow the progression of memory loss and cognitive decline in individuals with amnestic mild cognitive impairment (aMCI), a significant risk factor for Alzheimer's disease (AD), a new study suggests. A randomized, placebo-controlled trial showed treatment with lithium, an old drug historically used to treat bipolar d...

Olanzapine - olanzapine injection, powder, lyophilized, for solution-AuroMedics Pharma LLC
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9c745e2e-89d3-44d4-906e-704705c33310

Nov 18th, 2021 - Boxed Warning Section Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Analyses of seventeen placebo-controlled trials (modal duration of 10 weeks), largely in patients taking atypical antipsychotic drugs, revealed a risk of death in drug-treated patients of between 1.6 to 1.7 times the risk of death...

Quetiapine fumarate - quetiapine fumarate tablet-Bryant Ranch Prepack
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f75a4d38-ea0e-4780-abf2-67672894a11b

Mar 7th, 2022 - SPL PRODUCT DATA ELEMENTS SECTION Structure quetiapine-fig1 quetiapine-fig2 Recent Major Changes Section Warnings and Precautions (5.20) 09/2020 BOXED WARNING SECTION Increased Mortality in Elderly Patients with Dementia-Related Psychosis Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death [ see Warnings an...

Fast Food Linked to Increased Dementia Risk
https://www.medscape.com/viewarticle/978125

Jul 27th, 2022 - A diet high in ultraprocessed foods (UPFs) is linked to an increased risk for dementia, new research suggests. In a prospective cohort study, individuals who consumed the highest amounts of soft drinks, chips, and other UPFs had the highest risk of developing dementia compared with their counterparts who consumed the lowest amounts of these foods...

Exploring cognitive and brain oxygenation changes over a 1-year period in physically ac...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9361664
BMC Geriatrics; Talamonti D, Gagnon C et. al.

Aug 9th, 2022 - Aging is associated with an increased likelihood of developing dementia, but a growing body of evidence suggests that certain modifiable risk factors may help prevent or delay dementia onset. Among these, physical activity (PA) has been linked to better cognitive performance and brain functions in healthy older adults and may contribute to preventing dement...

Does the SORG Orthopaedic Research Group Hip Fracture Delirium Algorithm Perform Well o...
https://doi.org/10.1097/CORR.0000000000002246
Clinical Orthopaedics and Related Research; Oosterhoff JHF, Oberai T et. al.

May 14th, 2022 - Postoperative delirium in patients aged 60 years or older with hip fractures adversely affects clinical and functional outcomes. The economic cost of delirium is estimated to be as high as USD 25,000 per patient, with a total budgetary impact between USD 6.6 to USD 82.4 billion annually in the United States alone. Forty percent of delirium episodes are preventable, and accurate risk stra...

Quetiapine fumarate - quetiapine fumarate tablet-Ascend Laboratories, LLC
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3112a006-1c61-47f2-84f5-9a7670d09c9b

Aug 4th, 2022 - BOXED WARNING SECTION Increased Mortality in Elderly Patients with Dementia-Related Psychosis Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death [ see Warnings and Precautions (5.1) ]. Quetiapine is not approved for the treatment of patients with dementia-related psychosis [ see Warnings and Precautions...

Dementia Risk Not Higher in ADT-Treated Prostate CA Patients
https://www.staging.medscape.com/viewarticle/885249

Sep 6th, 2017 - There was no increased risk for Alzheimer's disease following treatment with androgen deprivation therapy (ADT) in a group of men age 67 years and older with advanced prostate cancer, a new study concludes. The patients were enrolled in Medicare. The finding contrasts with recent reports suggesting that there is an increased risk for cognitive impairment in patients who receive AD...

Dementia Risk Not Higher in ADT-Treated Prostate CA Patients
https://www.medscape.com/viewarticle/885249

Sep 6th, 2017 - There was no increased risk for Alzheimer's disease following treatment with androgen deprivation therapy (ADT) in a group of men age 67 years and older with advanced prostate cancer, a new study concludes. The patients were enrolled in Medicare. The finding contrasts with recent reports suggesting that there is an increased risk for cognitive impairment in patients who receive AD...

Projected Dementia Epidemic Averted?
https://www.medscape.com/viewarticle/850437

Sep 2nd, 2015 - Despite an aging population, dementia cases may be leveling off in western Europe thanks to better education and living conditions and greater attention to vascular disease, say the authors of a new paper. Current estimates of the number of dementia cases in western European countries are based on old studies from the 1980s, they note in a Policy View article published online Augu...

Quetiapine fumarate - quetiapine fumarate tablet-Quality Care Products, LLC
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fb4e8fe9-773f-45cc-9f67-3a668d16ce66

Jul 13th, 2022 - Recent Major Changes Section Warnings and Precautions (5.20) 09/2020 BOXED WARNING SECTION Increased Mortality in Elderly Patients with Dementia-Related Psychosis Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death [ see Warnings and Precautions (5.1) ]. Quetiapine is not approved for the treatment of patient...

Robots Used to Engage Seniors in Activities
https://www.clinicaladvisor.com/home/topics/geriatrics-information-center/robots-used-engage-seniors-activities/

May 4th, 2022 - In this installment, the leadership team at the Gerontological Advanced Practice Nurses Association () highlights the most important published literature that impacts geriatric practice. This month, GAPNA Past-President Sherry A. Greenberg, PhD, RN, GNP-BC, FGSA, FNAP, FAANP, FAAN, reviews 3 studies: the first on the use of robots to engage seniors in activities; the second on transitioning fro...

Quetiapine fumarate - quetiapine fumarate tablet, film coated-Bryant Ranch Prepack
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9a024071-e620-48e8-9f22-d4cda5dc5ab1

May 2nd, 2022 - SPL PRODUCT DATA ELEMENTS SECTION quetiapine-structure quetiapine-fig-1 quetiapine-fig-2 Boxed Warning Section Increased Mortality in Elderly Patients with Dementia-Related Psychosis Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death [see Warnings and Precautions (5.1)]. Quetiapine is not approved for the tr...