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SARS-CoV-2 and Nervous System - Neurological Manifestations in Patients With COVID-19: A Systematic Review

Coronavirus (CoV) is a virus infectious disease with a considerable spectrum of clinical presentations. Symptoms ranged from asymptomatic infection to severe pneumonia that may lead to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and several clinical complications. Neurologic symptoms related to CoV have been described recently in the literature. The ...

Early neurological manifestations of hospitalized COVID-19 patients

Neurological manifestations can occur during coronavirus disease 19 (COVID-19). Several pathogenic mechanisms have been hypothesized, without conclusive results. In this study, we evaluated the most frequent neurological symptoms in a cohort of hospitalized COVID-19 patients, and also investigated the possible relationship between plasmatic inflammatory indices and olfactory disor...

Two immunocompromised patients with diffuse alveolar hemorrhage as a complication of severe COVID-19

Diffuse alveolar hemorrhage (DAH) is a severe and potentially life-threatening disease manifestation. Besides autoimmune diseases such as anti-neutrophil cytoplasmatic antibody (ANCA) associated vasculitis and anti-glomerular basement membrane (anti-GBM) syndrome pulmonary viral infections are also known to be culprits of DAH. The coronavirus disease 2019 (COVID-19) pandemic confronts he...

CDC Symptoms of Coronavirus (COVID-19)
Centers for Disease Control & Prevention;

People with COVID-19 have had a wide range of symptoms reported – ranging from mild symptoms to severe illness.

COVID-19 Testing: The Threat of False-Negative Results
Mayo Clinic Proceedings;

As health care systems around the world attempt to cope with the coronavirus disease 2019 (COVID-19) “tsunami,” concerns about ongoing spread of disease from individuals who are infected without symptoms have been raised.

The pandemic could put your doctor out of business
The Washington Post

Some coronavirus patients experience a mild fever or never know they were infected. Others crash quickly and unpredictably, five to 12 days after developing symptoms; every doctor on the front lines has been humbled by a patient who is fine in the morning and on a ventilator in the afternoon. To combat this problem, primary-care teams at my hospital are trying something new: calli...

Science points to causes of COVID-19
UN Environment Programme;

May 21st, 2020 - The coronavirus (COVID-19) is a zoonotic disease. Zoonotic diseases are transmitted between animals and humans. Diseases passed from animals to humans are a significant threat to human health. When the symptoms are serious, our lack of prior exposure means humans have no existing antibodies to defend themselves against the disease. Recent zoonotic disease outbreaks include Severe ...

AAAAI Resources for Clinicians During the COVID-19 Pandemic

As the coronavirus disease 2019 (COVID-19) spreads across the globe, we recognize the importance of our roles as healthcare providers, particularly to patients known for asthma, other allergic conditions, or immune deficiencies who may be at a higher risk of experiencing severe symptoms from the disease. The same way that you are committed to your patients, practices, and communit...

CDC confirms six coronavirus symptoms showing up in patients over and over
Washington Post; Fritz A

Apr 26th, 2020 - The Centers for Disease Control and Prevention added six symptoms of the novel coronavirus to its list, suggesting health experts are learning more about the growing number of ways physicians see the virus affecting patients.

AHA Coronavirus (COVID-19) Resources
American Heart Association;

Coronavirus disease 2019 (COVID-19) is a respiratory illness that can spread from person to person, which has affected people in many countries. Here are some resources to find more information. The American Heart Association is advising caution and preparation for people who have heart disease or who have survived a stroke. Based on current information, it appears elderly people with co...

Lung Health & Diseases: Coronavirus Disease (COVID-19)

COVID-19 is a lung disease caused by a novel coronavirus first detected in late 2019. COVID-19 and its symptoms can range from mild to severe. Anyone can get COVID-19, but some individuals are more at risk for severe disease than others. There is currently no specific treatment other than supportive care available. The majority of people recover from COVID-19 within a few weeks, b...

Coronavirus patients arrived in France without symptoms

Jan 25th, 2020 - PARIS (Reuters) - Two of the three Chinese nationals in France who have been diagnosed with the Wuhan coronavirus arrived without showing symptoms, doctors at a Paris hospital said on Saturday. A woman wears a face mask on the Trocadero esplanade in front of the Eiffel Tower in Paris, France, January 25, 2020, as France confirmed three cases of the new coronavirus. REUTERS/...

First Case of 2019 Novel Coronavirus in the United States.
The New England Journal of Medicine; Holshue ML, DeBolt C et. al.

Jan 31st, 2020 - An outbreak of novel coronavirus (2019-nCoV) that began in Wuhan, China, has spread rapidly, with cases now confirmed in multiple countries. We report the first case of 2019-nCoV infection confirmed in the United States and describe the identification, diagnosis, clinical course, and management of the case, including the patient's initial mild symptoms at presentation with progres...

Transmission of MERS-coronavirus in household contacts.
The New England Journal of Medicine; Drosten C, Meyer B et. al.

Aug 27th, 2014 - Strategies to contain the Middle East respiratory syndrome coronavirus (MERS-CoV) depend on knowledge of the rate of human-to-human transmission, including subclinical infections. A lack of serologic tools has hindered targeted studies of transmission. We studied 26 index patients with MERS-CoV infection and their 280 household contacts. The median time from the onset of symptoms ...

Recommendation Regarding the Use of Cloth Face Coverings, Especially in Areas of Significant Community-Based Transmission
Centers for Disease Control and Prevention;

CDC continues to study the spread and effects of the novel coronavirus across the United States. We now know from recent studies that a significant portion of individuals with coronavirus lack symptoms (“asymptomatic”) and that even those who eventually develop symptoms (“pre-symptomatic”) can transmit the virus to others before showing symptoms. This means t...

Coronavirus Disease 2019 in Children - United States, February 12-April 2, 2020.
MMWR. Morbidity and Mortality Weekly Report;

Apr 9th, 2020 - As of April 2, 2020, the coronavirus disease 2019 (COVID-19) pandemic has resulted in >890,000 cases and >45,000 deaths worldwide, including 239,279 cases and 5,443 deaths in the United States (1,2). In the United States, 22% of the population is made up of infants, children, and adolescents aged

Coronavirus immunoreactivity in individuals with a recent onset of psychotic ...
Schizophrenia Bulletin; Severance EG, Dickerson FB et. al.

Jun 5th, 2009 - Prenatal influenza exposure increases the risk for schizophrenia and brings to question how other respiratory viruses may contribute to neuropsychiatric disease etiopathology. Human coronaviruses cause respiratory infections that range in seriousness from common colds to severe acute respiratory syndrome. Like influenza, coronaviruses can be neurotropic. To test for associations b...

Two deletion variants of Middle East respiratory syndrome coronavirus found in a...
Archives of Virology; Xie Q, Cao Y et. al.

Apr 19th, 2017 - Significant sequence variation of Middle East respiratory syndrome coronavirus (MERS CoV) has never been detected since it was first reported in 2012. A MERS patient came from Korea to China in late May 2015. The patient was 44 years old and had symptoms including high fever, dry cough with a little phlegm, and shortness of breath, which are roughly consistent with those associate...

Alert for non-respiratory symptoms of Coronavirus Disease 2019 (COVID-19)...
Journal of Medical Virology; Lu S, Lin J et. al.

Mar 18th, 2020 - At present, Coronavirus Disease 2019 (COVID-19) is rampaging around the world. However, asymptomatic carriers intensified the difficulty of prevention and management. Here we reported the screening, clinical feathers, and treatment process of a family cluster involving three COVID-19 patients. The discovery of the first asymptomatic carrier in this family cluster depends on the repeated ...

Time Kinetics of Viral Clearance and Resolution of Symptoms in Novel Coronavi...
American Journal of Respiratory and Critical Care Medicine; Chang , Mo G et. al.

Mar 22nd, 2020 - Time Kinetics of Viral Clearance and Resolution of Symptoms in Novel Coronavirus Infection.|2020|Chang ,Mo G,Yuan X,Tao Y,Peng X,|