American Journal of Ophthalmology; Choi EY, Kim M et. al.
Jul 10th, 2022 - To investigate the association between intermittent fasting and age-related macular degeneration (AMD) in the general older adult population. A cross-sectional study using a population-based, government-led survey data, Korean National Health and Nutrition Examination Survey (KNHANES). A total of 4504 individuals aged ≥55 years with comprehensive data including meal frequency and ...
Nov 1st, 2018 - In some people, AMD advances so slowly that vision loss does not occur for a long time. In others, the disease progresses faster and may lead to a loss of vision in one or both eyes. As AMD progresses, a blurred area near the center of vision is a common symptom. Over time, the blurred area may grow larger or you may develop blank spots in your central vision. Objects also may not appear to be ...
Jul 26th, 2019 - Age-related macular degeneration (AMD) is a disease that blurs the sharp, central vision you need for “straight-ahead” activities such as reading, sewing, and driving. AMD affects the macula, the part of the eye that allows you to see fine detail. AMD causes no pain.
Jul 16th, 2019 - Age-related macular degeneration is an eye disease that is a leading cause of vision loss in older people in developed countries. The vision loss usually becomes noticeable in a person's sixties or seventies and tends to worsen over time.
JAMA Klein BE, Howard KP et. al.
Jan 5th, 2013 - Aspirin is widely used for relief of pain and for cardioprotective effects. Its use is of concern to ophthalmologists when ocular surgery is being considered and also in the presence of age-related macular degeneration (AMD). To examine the association of regular aspirin use with incidence of AMD. The Beaver Dam Eye Study, a longitudinal population-based study of age-related eye d...
JAMA Ophthalmology; Brelén ME, Ng DS et. al.
Mar 21st, 2019 - The Question of Prescribing Calcium Supplements to Patients at High Risk of Age-Related Macular Degeneration.|2019|Brelén ME,Ng DS,Cheung CY,|
American Journal of Ophthalmology; Bikbov MM, Zainullin RM et. al.
Oct 14th, 2019 - To assess the prevalence of age-related macular degeneration (AMD) in a Russian population. Population-based prevalence assessment. The Ural Eye and Medical Study was conducted in a rural and urban area in the Russian republic of Bashkortostan. The study included 5,899 participants aged 40+ years old. AMD, defined according to the Beckman Initiative for Macular Research, wa...
Neurology Ahn J, Lee JY et. al.
Aug 17th, 2018 - To analyze the relationship between retinal thinning and nigral dopaminergic loss in de novo Parkinson disease (PD). Forty-nine patients with PD and 54 age-matched controls were analyzed. Ophthalmologic examination and macula optical coherence tomography scans were performed with additional microperimetry, N-(3-[18F]fluoropropyl)-2-carbomethoxy-3-(4-iodophenyl) nortropane PET, and 3T MRI scans ...
StatPearls; Surabhi Ruia, Evan J. Kaufman
Aug 9th, 2021 - Age-related macular degeneration (ARMD) is the most common cause of blindness prevalent in developed countries, particularly in people older than 60 years. It accounts for 8.7% of all types of blindness worldwide. This activity highlights the clinical features, symptoms, imaging characteristics of the disease, and the role of the interprofessional team in its management. Objective...
Journal of Vision; Verghese P, Ghahghaei S et. al.
Dec 30th, 2022 - Individuals with macular degeneration typically lose vision in the central region of one or both eyes. A binocular scotoma occurs when vision loss occurs in overlapping locations in both eyes, but stereopsis is impacted even in the non-overlapping region wherever the visual field in either eye is affected. We used a novel stereoperimetry protocol to measure local stereopsis across...
JAMA Ophthalmology; Larsen M
Dec 23rd, 2022 - Nitrates and Age-Related Macular Degeneration.|2022|Larsen M,|drug therapy,
Nature Reviews. Drug Discovery; Villanueva MT
Jul 9th, 2022 - Two-pronged approach for macular degeneration.|2022|Villanueva MT,|drug therapy,
Vision Research; Vullings C, Lively Z et. al.
Aug 22nd, 2022 - Macular degeneration (MD) compromises both high-acuity vision and eye movements when the foveal regions of both eyes are affected. Individuals with MD adapt to central field loss by adopting a preferred retinal locus (PRL) for fixation. Here, we investigate how individuals with bilateral MD use eye movements to search for targets in a visual scene under realistic binocular viewing...
Progress in Retinal and Eye Research; Merle DA, Sen M et. al.
Dec 14th, 2022 - Despite comprehensive research efforts over the last decades, the pathomechanisms of age-related macular degeneration (AMD) remain far from being understood. Large-scale genome wide association studies (GWAS) were able to provide a defined set of genetic aberrations which contribute to disease risk, with the strongest contributors mapping to distinct regions on chromosome 1 and 10...
Current Opinion in Ophthalmology; Bhandari S, Chew EY
Dec 10th, 2022 - Cataract surgery improves vision loss due to cataracts in eyes with co-existing age-related macular degeneration (AMD), but whether surgery itself pose an increased risk for the progression of AMD has been of concern to both physicians and their patients. This review describes evidence on cataract surgery and its impact on the progression of AMD. Recent evidence suggests that cata...
Investigative Ophthalmology & Visual Science; Guénot J, Trotter Y et. al.
Nov 16th, 2022 - Optic flow processing was characterized in patients with macular degeneration (MD). Twelve patients with dense bilateral scotomas and 12 age- and gender-matched control participants performed psychophysical experiments. Stimuli were dynamic random-dot kinematograms projected on a large screen. For each component of optic flow (translational, radial, and rotational), we estimated m...
JAMA Ophthalmology; Rein DB, Wittenborn JS et. al.
Nov 4th, 2022 - Age-related macular degeneration (AMD) is a leading cause of vision loss and blindness. AMD prevalence has not been estimated for the US in over a decade and early-stage AMD prevalence estimates are scarce and inconsistently measured. To produce estimates of early- and late-stage AMD prevalence overall and by age, gender, race and ethnicity, county, and state. The study team condu...
Autophagy Kaarniranta K, Blasiak J et. al.
Apr 26th, 2022 - Age-related macular degeneration (AMD) is the leading cause of visual impairment in the aging population with limited understanding of its pathogenesis and a lack of effective treatment. The progression of AMD is initially characterized by atrophic alterations in the retinal pigment epithelium, as well as the formation of lysosomal lipofuscin and extracellular drusen deposits. Dam...
The New England Journal of Medicine; Apte RS
Aug 5th, 2021 - Age-Related Macular Degeneration.|2021|Apte RS,|diagnosis,drug therapy,diagnostic imaging,pathology,antagonists & inhibitors,
Seminars in Ophthalmology; Fairbanks AM, Husain D
Jan 6th, 2023 - Age-related macular degeneration is a leading cause of blindness in patients aged 50 years and older. Prior to the 21st century, there were no effective treatments for this devastating disease. However, the last 20 years have heralded the development of treatments for both the nonexudative and exudative forms. The invention of AREDS vitamin supplements and anti-VEGF therapies fore...