Nov 25th, 2018 - Maintenance intravenous fluids (IVFs) are used to provide critical supportive care for children who are acutely ill. IVFs are required if sufficient fluids cannot be provided by using enteral administration for reasons such as gastrointestinal illness, respiratory compromise, neurologic impairment, a perioperative state, or being moribund from an acute or chro.
Pediatrics Feld LG, Neuspiel DR et. al.
Nov 27th, 2018 - Maintenance intravenous fluids (IVFs) are used to provide critical supportive care for children who are acutely ill. IVFs are required if sufficient fluids cannot be provided by using enteral administration for reasons such as gastrointestinal illness, respiratory compromise, neurologic impairment, a perioperative state, or being moribund from an acute or chro...
Pediatrics Wang J, Xu E et. al.
Dec 31st, 2013 - To assess evidence from randomized controlled trials (RCTs) on the safety of isotonic versus hypotonic intravenous (IV) maintenance fluids in hospitalized children. We searched PubMed, Embase, Cochrane Library, and clinicaltrials.gov (up to April 11, 2013) for RCTs that compared isotonic to hypotonic maintenance IV fluid therapy in hospitalized ...
BMC Pediatrics; Saba TG, Fairbairn J et. al.
Sep 28th, 2011 - Isotonic saline has been proposed as a safer alternative to traditional hypotonic solutions for intravenous (IV) maintenance fluids to prevent hyponatremia. However, the optimal tonicity of maintenance intravenous fluids in hospitalized children has not been determined. The objective of this study was to estimate and compare the rates of c...
Paediatrics and International Child Health; Duke T
Jun 1st, 2016 - Maintenance intravenous fluids for children: enough evidence, now for translation and action.|2016|Duke T,|methods,adverse effects,methods,administration & dosage,administration & dosage,administration & dosage,therapy,
Journal of Tropical Pediatrics; S K R, Dakshayani B et. al.
Mar 23rd, 2017 - We aimed to compare the effect of two different intravenous fluid regimes on the incidence of hyponatremia in children. Children 1 month to 18 years of age, admitted to pediatric intensive care unit (PICU) of a tertiary care medical college hospital were randomized to receive either isotonic fluid (0.9% saline in 5% dextrose) at the standard maintenance rate or hypot...
Journal of Hospital Medicine; Girdwood ST, Parker MW et. al.
Feb 27th, 2019 - The study aimed to compare the tumor response to and complications of doxorubicin-eluting CalliSphere bead-transarterial chemoembolization (DEB-TACE) using small- and medium-sized beads in patients with hepatocellular carcinoma (HCC) who underwent multiple rounds of oncology therapies. Sixty patients with intermediate stage HCC who had previously received multiple oncology therapies underwent D...
American Family Physician; Costlow L
Aug 15th, 2019 - Maintenance Intravenous Fluids in Children: AAP Provides Recommendations.|2019|Costlow L,|
JAMA Freedman SB, Willan AR et. al.
Apr 30th, 2016 - Gastroenteritis is a common pediatric illness. Electrolyte maintenance solution is recommended to treat and prevent dehydration. Its advantage in minimally dehydrated children is unproven. To determine if oral hydration with dilute apple juice/preferred fluids is noninferior to electrolyte maintenance solution in children with mild gastroenteritis. Randomized,...
JAMA Pediatrics; Friedman JN, Beck CE et. al.
Mar 9th, 2015 - Use of hypotonic intravenous fluids for maintenance requirements is associated with increased risk of hyponatremia that results in morbidity and mortality in children. Clinical trial data comparing isotonic and hypotonic maintenance fluids in nonsurgical hospitalized pediatric patients outside intensive care units are lacking. To compare isotonic (sodiu...
Pediatric Emergency Care; Cavari Y, Pitfield AF et. al.
Nov 7th, 2013 - Intravenous maintenance fluid therapy aims to replace daily urinary and insensible losses for ill children in whom adequate enteric administration of fluids is contraindicated or infeasible. The traditional determination of fluid volumes and composition dates back to Holliday and Segar's seminal article from 1957, which describes the relationship between weight, ener...
The New England Journal of Medicine; Moritz ML, Ayus JC
Sep 30th, 2015 - Maintenance Intravenous Fluids in Acutely Ill Patients.|2015|Moritz ML,Ayus JC,|physiology,therapy,administration & dosage,
In a new evidence-based clinical guideline, the American Academy of Pediatrics (AAP) recommends isotonic intravenous fluids (IVFs) with appropriate potassium chloride and dextrose for most children aged 28 days to 18 years who require maintenance IVFs. Isotonic IVFs reduce the risk for hyponatremia, which can cause excess fluid in the brain, resulting in potentially ...
Nov 25th, 2018 - In a new evidence-based clinical guideline, the American Academy of Pediatrics (AAP) recommends isotonic intravenous fluids (IVFs) with appropriate potassium chloride and dextrose for most children aged 28 days to 18 years who require maintenance IVFs. Isotonic IVFs reduce the risk for hyponatremia, which can cause excess fluid in the brain, resulting in potentially ...
Journal of Paediatrics and Child Health; Tran MM, Tantsis EM et. al.
Mar 2nd, 2017 - The administration of intravenous fluids remains a common intervention for hospitalised children. Commonly used hypotonic fluids administered at maintenance rates provide 2-4 mmol/kg/day of sodium. Being hypotonic, the development of hyponatraemia remains a risk. The consequences of hyponatraemia are not insignificant, with possibilities of irreversible neurol...
The Cochrane Database of Systematic Reviews; McNab S, Ware RS et. al.
Dec 18th, 2014 - Maintenance intravenous fluids are frequently used in hospitalised children who cannot maintain adequate hydration through enteral intake. Traditionally used hypotonic fluids have been associated with hyponatraemia and subsequent morbidity and mortality. Use of isotonic fluid has been proposed to reduce complications. To establish and compare the risk of hypon...
Journal of Paediatrics and Child Health; McNab S
Apr 11th, 2016 - Intravenous fluids are frequently used in paediatrics but have been associated with significant adverse outcomes. Understanding the composition of fluid prescribed and administering an appropriate rate is essential for safe fluid administration, along with regular monitoring. Recent evidence has shown that using an isotonic fluid with a sodium concentration similar to plasma can d...
The Journal of Pediatrics; Neville KA, Sandeman DJ et. al.
Oct 12th, 2009 - To determine the importance of sodium content versus administration rate of intravenous fluids in the development of hyponatremia in postoperative children. In this prospective, randomized, nonblinded study, 124 children admitted for surgery received 0.9% (NS) or 0.45% (N/2) saline solution at 100% or 50% maintenance rates. Plasma electrolytes, osmolality, and...
Hospital Pediatrics; Rooholamini SN, Clifton H et. al.
Nov 22nd, 2017 - Improper use of maintenance intravenous fluids (IVFs) may cause serious hospital-acquired harm. We created an evidence-based clinical pathway to guide providers on the indications for IVF, its preferred composition, and appropriate clinical monitoring. Pathway implementation was supported by the creation of an electronic order set (PowerPlan) and hospital-wide education. Ou...
Journal of Hospital Medicine; Hall AM, Ayus JC et. al.
Aug 29th, 2018 -